[HTML][HTML] Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review

Z Vinarov, M Abdallah, JAG Agundez… - European Journal of …, 2021 - Elsevier
The absorption of oral drugs is frequently plagued by significant variability with potentially
serious therapeutic consequences. The source of variability can be traced back to …

Foundations of gastrointestinal-based drug delivery and future developments

JN Chu, G Traverso - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …

Novel nano-encapsulated probiotic agents: Encapsulate materials, delivery, and encapsulation systems

C Xu, Q Ban, W Wang, J Hou, Z Jiang - Journal of Controlled Release, 2022 - Elsevier
Gut microbes are closely associated with most human health. When ingested orally,
probiotics can effectively regulate the composition and quantity of human intestinal …

RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract

SS Srinivasan, A Alshareef, AV Hwang, Z Kang… - Science robotics, 2022 - science.org
Oral drug delivery of proteins is limited by the degradative environment of the
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Harnessing artificial intelligence for the next generation of 3D printed medicines

M Elbadawi, LE McCoubrey, FKH Gavins… - Advanced Drug Delivery …, 2021 - Elsevier
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced drug delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

[HTML][HTML] Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network

Z Vinarov, B Abrahamsson, P Artursson… - Advanced Drug Delivery …, 2021 - Elsevier
Although oral drug delivery is the preferred administration route and has been used for
centuries, modern drug discovery and development pipelines challenge conventional …

[HTML][HTML] Oral drug delivery strategies for development of poorly water soluble drugs in paediatric patient population

S Salunke, F O'Brien, DCT Tan, D Harris… - Advanced Drug Delivery …, 2022 - Elsevier
Selecting the appropriate formulation and solubility-enabling technology for poorly water
soluble drugs is an essential element in the development of formulations for paediatric …

Powering implantable and ingestible electronics

SY Yang, V Sencadas, SS You, NZX Jia… - Advanced functional …, 2021 - Wiley Online Library
Implantable and ingestible biomedical electronic devices can be useful tools for detecting
physiological and pathophysiological signals, and providing treatments that cannot be done …