The quinoline scaffold is prevalent in a variety of pharmacologically active synthetic and
natural compounds. The discovery of chloroquine, the most famous drug containing this …

Malaria is a disease that affects nearly 40% of the global population, and chemotherapy
remains the mainstay of its control strategy. The global malaria situation is increasingly …

Background: Artemisinin is a sesquiterpene lactone compound with a special peroxide
bridge that is tightly linked to the cytotoxicity involved in fighting malaria and cancer …

Heterocyclic motif is an important scaffold which has both industrial and pharmaceutical
applications. These motifs can be prepared using wide variety of reaction conditions such as …

Fluorescent probes are attractive tools for biology, drug discovery, disease diagnosis, and
environmental analysis. In bioimaging, these easy-to-operate and inexpensive probes can …

The biological activity of organic peroxides is usually associated with the antimalarial
properties of artemisinin and its derivatives. However, the analysis of published data …

Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …

Cancer and malaria are major health conditions around the world despite many strategies
and therapeutics available for their treatment. The most used strategy for the treatment of …

Artemisinin is a natural compound extracted from Artemisia species belonging to the
Asteraceae family. Currently, artemisinin and its derivatives are considered among the most …

Heme (Fe2+ protoporphyrin IX) is an essential molecule that has been implicated the potent
antimalarial action of artemisinin and its derivatives, although the source and nature of the …