Cell-cell fusion between eukaryotic cells is a general process involved in many
physiological and pathological conditions, including infections by bacteria, parasites, and …

The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental
cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways …

As the COVID-19 pandemic continues to spread, investigating the processes underlying the
interactions between SARS-CoV-2 and its hosts is of high importance. Here, we report the …

The high transmissibility of SARS-CoV-2 is related to abundant replication in the upper
airways, which is not observed for the other highly pathogenic coronaviruses SARS-CoV …

The type II transmembrane serine proteases TMPRSS2 and HAT can cleave and activate
the spike protein (S) of the severe acute respiratory syndrome coronavirus (SARS-CoV) for …

The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) can
be proteolytically activated by cathepsins B and L upon viral uptake into target cell …

Infection with human coronavirus 229E (HCoV-229E) is associated with the common cold
and may result in pneumonia in immunocompromised patients. The viral spike (S) protein is …

Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …

Summary Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in
humans and primates. Understanding how these viruses enter host cells could help to …

The novel human coronavirus EMC (hCoV-EMC), which recently emerged in Saudi Arabia,
is highly pathogenic and could pose a significant threat to public health. The elucidation of …