Toxoplasmic encephalitis in AIDS

BJ Luft, JS Remington - Clinical infectious diseases, 1992 - academic.oup.com
Involvement of the central nervous system (CNS) is common in patients with advanced
disease due to human immunodeficiency virus (HIV). Symptoms range from lethargy and …

Babesiosis

MJ Homer, I Aguilar-Delfin, SR Telford III… - Clinical microbiology …, 2000 - Am Soc Microbiol
Babesiosis is an emerging, tick-transmitted, zoonotic disease caused by hematotropic
parasites of the genus Babesia. Babesial parasites (and those of the closely related genus …

Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3-hydroxy-1, 4-naphthoquinone (566C80)

M Fry, M Pudney - Biochemical pharmacology, 1992 - Elsevier
The site of action of the antimalarial compound 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3-
hydroxy-1, 4-naphthoquinone (566C80), would appear to be the mitochondrial respiratory …

Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development

M Schlitzer - ChemMedChem: Chemistry Enabling Drug …, 2007 - Wiley Online Library
Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …

A mechanism for the synergistic antimalarial action of atovaquone and proguanil

IK Srivastava, AB Vaidya - Antimicrobial agents and …, 1999 - Am Soc Microbiol
ABSTRACT A combination of atovaquone and proguanil has been found to be quite
effective in treating malaria, with little evidence of the emergence of resistance when …

[HTML][HTML] Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS

W Hughes, G Leoung, F Kramer… - New England journal …, 1993 - Mass Medical Soc
Background Both trimethoprim-sulfamethoxazole and pentamidine are effective as
treatments for Pneumocystis carinii pneumonia, but adverse effects frequently limit their use …

Therapeutic advances in the topical treatment of cutaneous leishmaniasis: A review

M Azim, SA Khan, S Ullah, S Ullah… - PLoS neglected tropical …, 2021 - journals.plos.org
Cutaneous leishmaniasis has been endemic since decades. Millions of cases are reported
worldwide specially in developing and underdeveloped countries. There are 2 major types …

Giardia and giardiasis

RCA Thompson, JA Reynoldson, AHW Mendis - Advances in parasitology, 1993 - Elsevier
Publisher Summary This chapter provides an overview of Giardia and giardiasis. General
morphology of the trophozoite of Giardia duodenalis is shown diagrammatically. Scanning …

Antimalarial pharmacology and therapeutics of atovaquone

GL Nixon, DM Moss, AE Shone… - Journal of …, 2013 - academic.oup.com
Atovaquone is used as a fixed-dose combination with proguanil (Malarone) for treating
children and adults with uncomplicated malaria or as chemoprophylaxis for preventing …

Natural products and the development of selective antiprotozoal drugs

CW Wright, JD Phillipson - Phytotherapy Research, 1990 - Wiley Online Library
New drugs are urgently required for the treatment of amoebiasis, leishmaniasis, malaria and
trypanosomiasis. In this review the potential of natural plant products as a source of …