Antiplatelet agents for preventing pre‐eclampsia and its complications

L Duley, S Meher, KE Hunter… - … of systematic reviews, 2019 - cochranelibrary.com
Background Pre‐eclampsia is associated with deficient intravascular production of
prostacyclin, a vasodilator, and excessive production of thromboxane, a vasoconstrictor and …

Aspirin or heparin or both for improving pregnancy outcomes in women with persistent antiphospholipid antibodies and recurrent pregnancy loss

EN Hamulyák, LJJ Scheres… - Cochrane Database …, 2020 - cochranelibrary.com
Aspirin or heparin or both for improving pregnancy outcomes in women with persistent
antiphospholipid antibodies and recurrent pregnancy loss - Hamulyák, EN - 2020 | Cochrane …

Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled …

MK Hoffman, SS Goudar, BS Kodkany, M Metgud… - The Lancet, 2020 - thelancet.com
Background Preterm birth remains a common cause of neonatal mortality, with a
disproportionately high burden in low-income and middle-income countries. Meta-analyses …

[HTML][HTML] Evaluation of low-dose aspirin in the prevention of recurrent spontaneous preterm labour (the APRIL study): A multicentre, randomised, double-blinded …

AJ Landman, MA de Boer, L Visser, TAJ Nijman… - PLoS …, 2022 - journals.plos.org
Background Preterm birth is the leading cause of neonatal morbidity and mortality. The
recurrence rate of spontaneous preterm birth is high, and additional preventive measures …

Does low-dose aspirin initiated before 11 weeks' gestation reduce the rate of preeclampsia?

P Chaemsaithong, D Cuenca-Gomez, MN Plana… - American Journal of …, 2020 - Elsevier
Objective Data Preconception or early administration of low-dose aspirin might improve
endometrial growth, placental vascularization, and organogenesis. Most studies have …

Low-dose aspirin is associated with reduced spontaneous preterm birth in nulliparous women

M Andrikopoulou, SE Purisch, R Handal-Orefice… - American journal of …, 2018 - Elsevier
Background Preterm birth is one of the leading causes of perinatal morbidity and mortality.
Clinical data suggest that low-dose aspirin may decrease the rate of overall preterm birth …

Innate immune system at the maternal–fetal interface: mechanisms of disease and targets of therapy in pregnancy syndromes

P Triggianese, C Perricone… - American journal of …, 2016 - Wiley Online Library
The maternal–fetal interface is an immunologically unique site that allows the tolerance to
the allogenic fetus and maintains host defense against possible pathogens. Balanced …

[HTML][HTML] Recent advances in the prevention of preterm birth

JA Keelan, JP Newnham - F1000Research, 2017 - ncbi.nlm.nih.gov
Preterm birth (PTB) remains a major obstetric healthcare problem and a significant
contributor to perinatal morbidity, mortality, and long-term disability. Over the past few …

The great obstetrical syndromes and the placenta

MK Hoffman - BJOG: An International Journal of Obstetrics & …, 2023 - Wiley Online Library
Although historically pre‐eclampsia, preterm birth, abruption, fetal growth restriction and
stillbirth have been viewed as clinically distinct entities, a growing body of literature has …

Complications and safety of preconception low-dose aspirin among women with prior pregnancy losses

KA Ahrens, RM Silver, SL Mumford… - Obstetrics & …, 2016 - journals.lww.com
OBJECTIVE: To evaluate complications and safety of preconception low-dose aspirin in
1,228 US women (2007–2011). METHODS: Evaluation of the safety of low-dose aspirin in …