Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …

Coffee is one of the most popular beverages consumed worldwide. Roasted coffee is a
complex mixture of thousands of bioactive compounds, and some of them have numerous …

Background Several articles suggest that DNA methylation levels in blood relate to
Parkinson's disease (PD) but there is a need for a large-scale study that involves suitable …

Parkinson's disease (PD) is a complex neurodegenerative condition in which genetic and
environmental factors interact to contribute to its etiology. Remarkable progress has been …

DNA methylation is an epigenetic mechanism that is related to mammalian cellular
differentiation, gene expression regulation, and disease. In several studies, DNA …

Background Coffee is one of the most widely consumed stimulants worldwide and is
generally considered to be safe or even beneficial for health. However, increased risk of …

Major Depressive Disorder (MDD) is a growing disabling condition affecting around 280
million people worldwide. This complex entity is the result of the interplay between …

It has been 200 years since Parkinson's disease (PD) was first described, yet many aspects
of its etiopathogenesis remain unclear. PD is a progressive and complex neurodegenerative …

Parkinson's disease (PD) is the second most common neurodegenerative disorder with an
unclear etiology and no disease-modifying treatment to date. PD is considered a …

Coffee is one of the most popular beverages worldwide. Coffee contains bioactive
compounds that affect the human body such as caffeine, caffeic acid, chlorogenic acids …