[HTML][HTML] Diagnostics for COVID-19: moving from pandemic response to control
Diagnostics have proven to be crucial to the COVID-19 pandemic response. There are three
major methods for the detection of SARS-CoV-2 infection and their role has evolved during …
major methods for the detection of SARS-CoV-2 infection and their role has evolved during …
The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a prospective …
A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …
and spreading globally, including in populations with high vaccination rates. We aimed to …
SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells
ABSTRACT The novel SARS-CoV-2 Omicron variant (B. 1.1. 529), first found in early
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
Estimating infectiousness throughout SARS-CoV-2 infection course
INTRODUCTION Although post facto studies have revealed the importance of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …
[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …
fundamental components of the adaptive immune system are B cells (the source of …
An evidence review of face masks against COVID-19
The science around the use of masks by the public to impede COVID-19 transmission is
advancing rapidly. In this narrative review, we develop an analytical framework to examine …
advancing rapidly. In this narrative review, we develop an analytical framework to examine …
SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity
The causative agent of the COVID-19 pandemic, SARS-CoV-2, is steadily mutating during
continuous transmission among humans. Such mutations can occur in the spike (S) protein …
continuous transmission among humans. Such mutations can occur in the spike (S) protein …
[HTML][HTML] Characteristics of SARS-CoV-2 and COVID-19
B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
[HTML][HTML] Considerations for diagnostic COVID-19 tests
O Vandenberg, D Martiny, O Rochas… - Nature Reviews …, 2021 - nature.com
During the early phase of the coronavirus disease 2019 (COVID-19) pandemic, design,
development, validation, verification and implementation of diagnostic tests were actively …
development, validation, verification and implementation of diagnostic tests were actively …