We survey work that has been carried out in the attempts of biomathematicians to
understand the dynamic behavior of simple bacterial operons starting with the initial work of …

The lysis-lysogeny switch in E. coli due to infection from lambda phage has been extensively
studied and explained by scientists of molecular biology. The bacterium either survives with …

The lac operon in E. coli has been extensively studied by computational biologists. The
bacterium uses it to survive in the absence of glucose, utilizing lactose for growth. This paper …

To talk about the lysis-lysogeny switch, we need to talk about bacteriophage (or simply
phage) λ. And to talk about phage λ, we need to talk about bacteriophages (or simply …

The central tenet of molecular biology was put forward some half century ago, and though
modified in detail still stands in its basic form. Transcription of DNA produces messenger …

Glucose is the preferred carbon and energy source for E. coli, as well as for many other
organisms. Although this bacterium can also feed on other sugars, it only does so when …

Intrinsic noise is inherent to many biological processes and provokes variation in gene
expression in a population of isogenic cells leading to phenotypic diversity. Intrinsic noise is …

Tryptophan is one of the 20 amino acids out of which all proteins are made. Arguably,
tryptophan is the most expensive amino acid to synthesize, biochemically speaking …

The Goodwin model for operon dynamics (Goodwin, Adv Enzyme Regul 3: 425–438, 1965)
considers a large population of cells, each of which contains one copy of a particular …

As in other approaches, the first step for employing the CME formalism consists of picturing
the system to be analyzed as a set of chemical reactions. As discussed in previous chapters …