[HTML][HTML] The role of BCL-2 family proteins in regulating apoptosis and cancer therapy
S Qian, Z Wei, W Yang, J Huang, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Apoptosis, as a very important biological process, is a response to developmental cues or
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …
Mechanism of interaction between autophagy and apoptosis in cancer
The mechanisms of two programmed cell death pathways, autophagy, and apoptosis, are
extensively focused areas of research in the context of cancer. Both the catabolic pathways …
extensively focused areas of research in the context of cancer. Both the catabolic pathways …
Mechanism of ferroptosis and its role in type 2 diabetes mellitus
W Sha, F Hu, Y Xi, Y Chu, S Bu - Journal of diabetes research, 2021 - Wiley Online Library
Ferroptosis is a novel form of nonapoptotic regulated cell death (RCD). It features iron‐
dependent lipid peroxide accumulation accompanied by inadequate redox enzymes …
dependent lipid peroxide accumulation accompanied by inadequate redox enzymes …
Apoptosis in Alzheimer's disease: insight into the signaling pathways and therapeutic avenues
S Kumari, R Dhapola, DHK Reddy - Apoptosis, 2023 - Springer
Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …
[HTML][HTML] Reactive oxygen species and mitochondrial dynamics: the yin and yang of mitochondrial dysfunction and cancer progression
J Ježek, KF Cooper, R Strich - Antioxidants, 2018 - mdpi.com
Mitochondria are organelles with a highly dynamic ultrastructure maintained by a delicate
equilibrium between its fission and fusion rates. Understanding the factors influencing this …
equilibrium between its fission and fusion rates. Understanding the factors influencing this …
DRP1 interacts directly with BAX to induce its activation and apoptosis
A Jenner, A Peña‐Blanco, R Salvador‐Gallego… - The EMBO …, 2022 - embopress.org
The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at
mitochondria during apoptosis to mediate mitochondrial permeabilization and …
mitochondria during apoptosis to mediate mitochondrial permeabilization and …
[HTML][HTML] A cell's fate: an overview of the molecular biology and genetics of apoptosis
GC Cavalcante, AP Schaan, GF Cabral… - International journal of …, 2019 - mdpi.com
Apoptosis is one of the main types of regulated cell death, a complex process that can be
triggered by external or internal stimuli, which activate the extrinsic or the intrinsic pathway …
triggered by external or internal stimuli, which activate the extrinsic or the intrinsic pathway …
Ferritinophagy/ferroptosis: Iron‐related newcomers in human diseases
M Tang, Z Chen, D Wu, L Chen - Journal of cellular physiology, 2018 - Wiley Online Library
Nuclear receptor coactivator 4 mediated ferritinophagy is an autophagic phenomenon that
specifically involves ferritin to release intracellular free iron. Ferritinophagy is implicated in …
specifically involves ferritin to release intracellular free iron. Ferritinophagy is implicated in …
Apoptosis and its therapeutic implications in neurodegenerative diseases
NS Erekat - Clinical Anatomy, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
[HTML][HTML] Insights into SGLT2 inhibitor treatment of diabetic cardiomyopathy: focus on the mechanisms
K Huang, X Luo, B Liao, G Li, J Feng - Cardiovascular Diabetology, 2023 - Springer
Among the complications of diabetes, cardiovascular events and cardiac insufficiency are
considered two of the most important causes of death. Experimental and clinical evidence …
considered two of the most important causes of death. Experimental and clinical evidence …