As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …

Hydrogel has been widely used in modern biotherapeutics due to its excellent
biocompatibility, degradability, and high drug loading capacity. Among them, the …

Primary brain tumors are mostly managed using surgical resection procedures.
Nevertheless, in certain cases, a thin layer of tumors may remain outside of the resection …

Oral squamous cell carcinoma (OSCC) accounts for nearly 90% of oral cavity malignancies.
However, despite significant advances in the last four decades, little improvement has been …

Glioblastoma multiforme (GBM) is the most aggressive primary tumor of the central nervous
system and the diagnosis is often dismal. GBM pharmacological treatment is strongly limited …

Glioblastoma is one of the most aggressive brain tumors and is associated with a very low
overall median survival despite the current treatment. The standard of care used in clinic is …

The objective of this work was to develop an implantable therapeutic hydrogel that will
ensure continuity in treatment between surgery and radiochemotherapy for patients with …

Systemic drug delivery is the current clinically preferred route for cancer therapy. However,
challenges associated with tumor localization and off-tumor toxic effects limit the clinical …

The selective and efficient delivery of bioactive molecules to sites of interest remains a
formidable challenge in medicine. In recent years, it has been shown that stimuli-responsive …