2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease …

G Hansmann, M Koestenberger, TP Alastalo… - The Journal of Heart and …, 2019 - Elsevier
The European Pediatric Pulmonary Vascular Disease Network is a registered, non-profit
organization that strives to define and develop effective, innovative diagnostic methods and …

Current modulation of guanylate cyclase pathway activity—mechanism and clinical implications

G Grześk, A Nowaczyk - Molecules, 2021 - mdpi.com
For years, guanylate cyclase seemed to be homogenic and tissue nonspecific enzyme;
however, in the last few years, in light of preclinical and clinical trials, it became an …

[HTML][HTML] Pediatric pulmonary hypertension: definitions, mechanisms, diagnosis, and treatment

D Mukherjee, GG Konduri - Comprehensive Physiology, 2021 - ncbi.nlm.nih.gov
Pediatric pulmonary hypertension (PPH) is a multifactorial disease with diverse etiologies
and presenting features. Pulmonary hypertension (PH), defined as elevated pulmonary …

[HTML][HTML] Selexipag for the treatment of children with pulmonary arterial hypertension: first multicenter experience in drug safety and efficacy

G Hansmann, K Meinel, M Bukova… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND The European Pediatric Pulmonary Vascular Disease Network (EPPVDN)
investigated the safety and efficacy of add-on selexipag, an oral prostacyclin receptor …

[PDF][PDF] 2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease …

G Hansmann, M Koestenberger… - J Heart Lung …, 2019 - files.cdn-files-a.com
The European Pediatric Pulmonary Vascular Disease Network is a registered, non-profit
organization that strives to define and develop effective, innovative diagnostic methods and …

Treatment of pediatric pulmonary arterial hypertension: A focus on the NO‐sGC‐cGMP pathway

M Beghetti, M Gorenflo, DD Ivy… - Pediatric …, 2019 - Wiley Online Library
Objective While pulmonary arterial hypertension (PAH) is rare in infants and children, it
results in substantial morbidity and mortality. In recent years, prognosis has improved …

Acute vasoreactivity testing during cardiac catheterization of neonates with bronchopulmonary dysplasia-associated pulmonary hypertension

BS Frank, M Schäfer, A Grenolds, DD Ivy… - The Journal of …, 2019 - Elsevier
Objectives To assess whether better baseline pulmonary hemodynamics or positive acute
vasoreactivity testing (AVT) during cardiac catheterization are associated with improved …

[HTML][HTML] Full recovery of right ventricular systolic function in children undergoing bilateral lung transplantation for severe PAH

G Hansmann, F Diekmann, P Chouvarine, F Ius… - The Journal of Heart and …, 2022 - Elsevier
Background We investigated whether RV function recovers in children with pulmonary
arterial hypertension (PAH) and RV failure undergoing lung transplantation (LuTx). Methods …

Expression and clinical significance of circular RNA hsa_circ_0003416 in pediatric pulmonary arterial hypertension associated with congenital heart disease

Y Huang, D Su, B Ye, Y Huang, S Qin… - Journal of Clinical …, 2022 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) have been found to be involved in the
development of pulmonary arterial hypertension (PAH). However, their diagnostic value in …

Advances in targeted therapy for pulmonary arterial hypertension in children

L Li, X Zhu, X Chen, J Gao, C Ding, M Zhang… - European Journal of …, 2023 - Springer
Pulmonary arterial hypertension (PAH) is a rare and devastating disease of the pulmonary
vasculature with a high morbidity and mortality rate in infants and children. Currently …