Genes encoding subunits of SWI/SNF chromatin remodeling complexes are collectively
mutated in 20% of all human cancers. ARID1A is the SWI/SNF subunit gene that is most …

The AT-rich interaction domain 1A (ARID1A) are frequently mutates across a broad
spectrum of cancers. The majority of ARID1A mutations are inactivating mutations and lead …

Even though a detailed understanding of the proliferative characteristics of T lymphocytes is
imperative in many research fields, prior studies have never reached a consensus on these …

AT‐rich interactive domain‐containing protein 1A (ARID1A) loss‐of‐function mutation
accompanied by a loss of ARID1A protein expression is frequently observed in endometrial …

Background Standard platinum-based therapy for ovarian cancer is inefficient against
ovarian clear cell carcinoma (OCCC). OCCC is a distinct subtype of epithelial ovarian …

The application of immune checkpoint inhibitor (ICI) using monoclonal antibodies has
brought about a profound transformation in the clinical outcomes for patients grappling with …

Investigation of natural products is an attractive strategy to identify novel compounds for
cancer prevention and treatment. Numerous studies have shown the efficacy and safety of …

Mutations in subunits of the SWItch Sucrose Non-Fermentable (SWI/SNF) chromatin
remodeling complex occur in≈ 20% of cancers and represent a highly unmet medical need …

Soft tissue myoepithelial carcinoma is a rare tumor first reported in the salivary gland. There
is considerable tumor heterogeneity between pathology findings, tumor aggressiveness …

Gastric cancer (GC) is one of the most common and deadly cancers in the world. Some of
the most frequently mutated genes in gastric cancer are chromatin regulators. Notably, AT …