Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …

Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …

The complex life cycle of Plasmodium falciparum requires coordinated gene expression
regulation to allow host cell invasion, transmission, and immune evasion. Increasing …

Clonally variant expression of surface antigens allows the malaria parasite Plasmodium
falciparum to evade immune recognition during blood stage infection and secure malaria …

The asexual forms of the malaria parasite Plasmodium falciparum are adapted for chronic
persistence in human red blood cells, continuously evading host immunity using …

The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1),
which is expressed on the surface of P. falciparum-infected red blood cells, is a critical …

Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The
malaria parasite Plasmodium falciparum employs antigenic variation of the major surface …

In the past few years, several new protein post-translational modifications that use
intermediates in metabolism have been discovered. These include various acyl lysine …

A universal feature of metazoan sexual development is the generation of oocyte P granules
that withhold certain mRNA species from translation to provide coding potential for proteins …

Epigenetic regulatory mechanisms and their enzymes are promising targets for malaria
therapeutic intervention; however, the epigenetic component of gene expression in P …