Follicular dendritic cells (FDCs) are essential for high-affinity antibody production and for the
development of B cell memory. Historically, FDCs have been characterized as' …

Unlike T cells that recognize digested peptides, B cells recognize their cognate antigen in its
native form. The B cell receptor used in recognition can also be secreted to bind to antigens …

Exaggerated complement activation is a key event in the pathogenesis of a range of
autoimmune and inflammatory diseases. Complement Receptor 1 (CR1) has emerged as a …

Duffy antigen receptor for chemokines (DARC) expressed on red blood cells (RBCs)
influences plasma levels of HIV-1-suppressive and proinflammatory chemokines such as …

Despite the success of antiretroviral therapy (ART), it does not cure Human
Immunodeficiency Virus (HIV) and discontinuation results in viral rebound. Follicular …

Microglia, the immune cell of the brain, are implicated in cascades leading to neuronal loss
and cognitive decline in Alzheimer's disease (AD). Recent genome‐wide association …

The complement system, a key component of innate immunity, is a first-line defender against
foreign pathogens such as HIV-1. The role of the complement system in HIV-1 pathogenesis …

The immunomodulatory properties of yeast β-1, 3/1, 6 glucans are mediated through their
ability to be recognized by human innate immune cells. While several studies have …

Host immune components play both beneficial and pathogenic roles in human
immunodeficiency virus type 1 (HIV‐1) infection. During the initial stage of viral infection, a …

ABSTRACT Approximately 4.4% of the human genome is comprised of endogenous
retroviral sequences, a record of an evolutionary battle between man and retroviruses. Much …