Cell-penetrating peptides: classes, origin, and current landscape
F Milletti - Drug discovery today, 2012 - Elsevier
With more than ten new FDA approvals since 2001, peptides are emerging as an important
therapeutic alternative to small molecules. However, unlike small molecules, peptides on the …
therapeutic alternative to small molecules. However, unlike small molecules, peptides on the …
Cell penetrating peptides: The potent multi-cargo intracellular carriers
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …
Cell penetrating peptides: efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules
SM Farkhani, A Valizadeh, H Karami, S Mohammadi… - Peptides, 2014 - Elsevier
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …
challenge. The cellular membrane is very effective in its role as a selectively permeable …
Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery
T Jiang, Z Zhang, Y Zhang, H Lv, J Zhou, C Li, L Hou… - Biomaterials, 2012 - Elsevier
Dual-functional liposomes with pH-responsive cell-penetrating peptide (CPP) and active
targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of …
targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of …
[HTML][HTML] Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting
F Perche, VP Torchilin - Journal of drug delivery, 2013 - hindawi.com
Liposomes are delivery systems that have been used to formulate a vast variety of
therapeutic and imaging agents for the past several decades. They have significant …
therapeutic and imaging agents for the past several decades. They have significant …
Potential efficacy of cell-penetrating peptides for nucleic acid and drug delivery in cancer
A Bolhassani - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2011 - Elsevier
Cell penetrating peptides (CPPs) are short amphipathic and cationic peptides that are
rapidly internalized across cell membranes. They can be used to deliver molecular cargo …
rapidly internalized across cell membranes. They can be used to deliver molecular cargo …
Molecular engineering solutions for therapeutic peptide delivery
Proteins and their interactions in and out of cells must be well-orchestrated for the healthy
functioning and regulation of the body. Even the slightest disharmony can cause diseases …
functioning and regulation of the body. Even the slightest disharmony can cause diseases …
A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system
Tumor-oriented nanocarrier drug delivery approaches with pH-sensitivity have been
drawing considerable attentions over the years. Here we described a liposomal delivery …
drawing considerable attentions over the years. Here we described a liposomal delivery …
[HTML][HTML] Dual-sensitive antibacterial peptide nanoparticles prevent dental caries
P Zhang, S Wu, J Li, X Bu, X Dong, N Chen, F Li… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Dental caries is the most prevalent bacterial biofilm-induced disease. Current
clinical prevention and treatment agents often suffer from adverse effects on oral microbiota …
clinical prevention and treatment agents often suffer from adverse effects on oral microbiota …
pH-sensitive drug-delivery systems for tumor targeting
X He, J Li, S An, C Jiang - Therapeutic delivery, 2013 - Future Science
Drug-delivery system responses to stimuli have been well investigated recently. As pH
decrease is observed in most solid tumors, drug-delivery systems responsive to the slightly …
decrease is observed in most solid tumors, drug-delivery systems responsive to the slightly …