Cell-penetrating peptides: classes, origin, and current landscape

F Milletti - Drug discovery today, 2012 - Elsevier
With more than ten new FDA approvals since 2001, peptides are emerging as an important
therapeutic alternative to small molecules. However, unlike small molecules, peptides on the …

Cell penetrating peptides: The potent multi-cargo intracellular carriers

K Kardani, A Milani, S H. Shabani… - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

Cell penetrating peptides: efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules

SM Farkhani, A Valizadeh, H Karami, S Mohammadi… - Peptides, 2014 - Elsevier
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …

Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery

T Jiang, Z Zhang, Y Zhang, H Lv, J Zhou, C Li, L Hou… - Biomaterials, 2012 - Elsevier
Dual-functional liposomes with pH-responsive cell-penetrating peptide (CPP) and active
targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of …

[HTML][HTML] Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting

F Perche, VP Torchilin - Journal of drug delivery, 2013 - hindawi.com
Liposomes are delivery systems that have been used to formulate a vast variety of
therapeutic and imaging agents for the past several decades. They have significant …

Potential efficacy of cell-penetrating peptides for nucleic acid and drug delivery in cancer

A Bolhassani - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2011 - Elsevier
Cell penetrating peptides (CPPs) are short amphipathic and cationic peptides that are
rapidly internalized across cell membranes. They can be used to deliver molecular cargo …

Molecular engineering solutions for therapeutic peptide delivery

H Acar, JM Ting, S Srivastava, JL LaBelle… - Chemical Society …, 2017 - pubs.rsc.org
Proteins and their interactions in and out of cells must be well-orchestrated for the healthy
functioning and regulation of the body. Even the slightest disharmony can cause diseases …

A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system

Q Zhang, J Tang, L Fu, R Ran, Y Liu, M Yuan, Q He - Biomaterials, 2013 - Elsevier
Tumor-oriented nanocarrier drug delivery approaches with pH-sensitivity have been
drawing considerable attentions over the years. Here we described a liposomal delivery …

[HTML][HTML] Dual-sensitive antibacterial peptide nanoparticles prevent dental caries

P Zhang, S Wu, J Li, X Bu, X Dong, N Chen, F Li… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Dental caries is the most prevalent bacterial biofilm-induced disease. Current
clinical prevention and treatment agents often suffer from adverse effects on oral microbiota …

pH-sensitive drug-delivery systems for tumor targeting

X He, J Li, S An, C Jiang - Therapeutic delivery, 2013 - Future Science
Drug-delivery system responses to stimuli have been well investigated recently. As pH
decrease is observed in most solid tumors, drug-delivery systems responsive to the slightly …