Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Aortic dissection is an emergent medical condition, generally affecting the elderly,
characterized by a separation of the aortic wall layers and subsequent creation of a …

Remarkable progress has become especially apparent in aortic medicine in the last few
decades, leading to essential changes in how thoracic aortic dissection is understood and …

Aims Whether changes in endothelial tight junctions (TJs) lead to the formation of thoracic
aortic aneurysm and dissection (TAAD) and serve as an early indicator and therapeutic …

Abstract Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial
and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra-and …

Cardiovascular disease (CVD) and cancer are leading causes of morbidity and mortality
worldwide. Although conventionally managed as separate disease processes, recent …

The aorta is the largest artery in the body, delivering oxygenated blood from the left ventricle
to all organs. Dissection of the aorta is a lethal condition caused by a tear in the intimal layer …

Acute aortic syndromes (AASs) are deadly cardiovascular emergencies involving the
thoracic aorta. AASs are relatively rare conditions, have unspecific signs and symptoms …

We are constantly looking for new parameters and markers that can help in the assessment
of patients with various diseases, including cardiac disorders; this can translate into better …

Objectives In patients at low clinical probability of acute aortic syndromes (AASs), decision
on advanced aortic imaging is cumbersome. Integration of the aortic dissection detection risk …