Macrophages in inflammation, repair and regeneration

Y Oishi, I Manabe - International immunology, 2018 - academic.oup.com
Tissue injury triggers a complex series of cellular responses, starting from inflammation
activated by tissue and cell damage and proceeding to healing. By clearing cell debris …

The immunopathophysiology of endometriosis

LK Symons, JE Miller, VR Kay, RM Marks… - Trends in molecular …, 2018 - cell.com
Endometriosis is a chronic, inflammatory, estrogen-dependent disease characterized by the
growth of endometrial tissue outside of the uterine cavity. Although the etiology of …

Endometriosis: pathogenesis and treatment

P Vercellini, P Viganò, E Somigliana… - Nature Reviews …, 2014 - nature.com
Endometriosis is defined as the presence of endometrial-type mucosa outside the uterine
cavity. Of the proposed pathogenic theories (retrograde menstruation, coelomic metaplasia …

Tumor-associated macrophages: role in cancer development and therapeutic implications

A Salmaninejad, SF Valilou, A Soltani, S Ahmadi… - Cellular oncology, 2019 - Springer
Abstract Background Tumor-associated macrophages (TAMs) are known to play important
roles in the initiation and progression of human cancers, as well as in angiogenesis. TAMs …

Endometriosis-associated macrophages: origin, phenotype, and function

C Hogg, AW Horne, E Greaves - Frontiers in endocrinology, 2020 - frontiersin.org
Endometriosis is a complex, heterogeneous, chronic inflammatory condition impacting~ 176
million women worldwide. It is associated with chronic pelvic pain, infertility, and fatigue, and …

Biomarkers for the noninvasive diagnosis of endometriosis: state of the art and future perspectives

CV Anastasiu, MA Moga, A Elena Neculau… - International journal of …, 2020 - mdpi.com
Background: Early and accurate diagnosis of endometriosis is crucial for the management of
this benign, yet debilitating pathology. Despite the advances of modern medicine, there is no …

The metastasis-promoting roles of tumor-associated immune cells

HA Smith, Y Kang - Journal of molecular medicine, 2013 - Springer
Tumor metastasis is driven not only by the accumulation of intrinsic alterations in malignant
cells, but also by the interactions of cancer cells with various stromal cell components of the …

Involvement of immune cells in the pathogenesis of endometriosis

G Izumi, K Koga, M Takamura, T Makabe… - Journal of Obstetrics …, 2018 - Wiley Online Library
Endometriosis is characterized by the implantation and growth of endometriotic tissues
outside the uterus. It is widely accepted the theory that endometriosis is caused by the …

Endometriosis, a disease of the macrophage

A Capobianco, P Rovere-Querini - Frontiers in immunology, 2013 - frontiersin.org
Endometriosis, a common cause of pelvic pain and female infertility, depends on the growth
of vascularized endometrial tissue at ectopic sites. Endometrial fragments reach the …

Can endometriosis-related oxidative stress pave the way for new treatment targets?

L Cacciottola, J Donnez, MM Dolmans - International journal of molecular …, 2021 - mdpi.com
Endometriosis is a disease of reproductive age characterized by chronic pelvic pain and
infertility. Its pathogenesis is complex and still partially unexplained. However, there is …