The mechanisms of cyclophosphamide-induced testicular toxicity and the protective agents
E Ghobadi, M Moloudizargari, MH Asghari… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Cyclophosphamide (CP) is an alkylating antineoplastic agent with known
toxicity to the male reproductive system. Areas covered: This review summarizes the known …
toxicity to the male reproductive system. Areas covered: This review summarizes the known …
Immunomodulating tellurium compounds as anti-cancer agents
B Sredni - Seminars in cancer biology, 2012 - Elsevier
Tellurium is a rare element, which has been regarded as a toxic, non-essential trace
element; its biological role, if any, has not been clearly established to date. The investigation …
element; its biological role, if any, has not been clearly established to date. The investigation …
Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model
Background: Every year, men use cyclophosphamide to treat various cancers and
autoimmune diseases. On the one hand, this chemotherapy often has the beneficial effect of …
autoimmune diseases. On the one hand, this chemotherapy often has the beneficial effect of …
PM2. 5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse
L Zhou, X Su, B Li, C Chu, H Sun, N Zhang… - Ecotoxicology and …, 2019 - Elsevier
Exposure to ambient fine particular matter (PM2. 5) has been clearly associated with male
reproductive disorders. However, very limited toxicological studies were carried out to …
reproductive disorders. However, very limited toxicological studies were carried out to …
Classification of mouse sperm motility patterns using an automated multiclass support vector machines model
SG Goodson, Z Zhang, JK Tsuruta, W Wang… - Biology of …, 2011 - academic.oup.com
Vigorous sperm motility, including the transition from progressive to hyperactivated motility
that occurs in the female reproductive tract, is required for normal fertilization in mammals …
that occurs in the female reproductive tract, is required for normal fertilization in mammals …
Astaxanthin inhibits cytotoxic and genotoxic effects of cyclophosphamide in mice germ cells
DN Tripathi, GB Jena - Toxicology, 2008 - Elsevier
Cyclophosphamide (CP), an alkylating agent used in the treatment of several cancers as
well as an immunosuppressant in rheumatoid arthritis. It is used against several cancers due …
well as an immunosuppressant in rheumatoid arthritis. It is used against several cancers due …
Toxic effect of cyclophosphamide on sperm morphology, testicular histology and blood oxidant‐antioxidant balance, and protective roles of lycopene and ellagic acid
AO Çeribaşi, G Türk, M Sönmez… - Basic & Clinical …, 2010 - Wiley Online Library
In this study, the toxic effect of cyclophosphamide (CP) on sperm morphology, testicular
histology and blood oxidant–antioxidant balance, and protective roles of lycopene (LC) and …
histology and blood oxidant–antioxidant balance, and protective roles of lycopene (LC) and …
Antiperoxidative and anti-apoptotic effects of lycopene and ellagic acid on cyclophosphamide-induced testicular lipid peroxidation and apoptosis
The present study was conducted to investigate the possible protective effects of lycopene
(LC) and ellagic acid (EA) on cyclophosphamide (CP)-induced testicular and spermatozoal …
(LC) and ellagic acid (EA) on cyclophosphamide (CP)-induced testicular and spermatozoal …
Metabolic substrates exhibit differential effects on functional parameters of mouse sperm capacitation
Although substantial evidence exists that sperm ATP production via glycolysis is required for
mammalian sperm function and male fertility, conflicting reports involving multiple species …
mammalian sperm function and male fertility, conflicting reports involving multiple species …
Protective effect of Satureja montana extract on cyclophosphamide-induced testicular injury in rats
AM Abd El Tawab, NN Shahin… - Chemico-Biological …, 2014 - Elsevier
The present study investigated the protective effect of Satureja montana extract against
cyclophosphamide-induced testicular injury in rats. Total phenolic and flavonoid contents of …
cyclophosphamide-induced testicular injury in rats. Total phenolic and flavonoid contents of …