Immobilization of l-Asparaginase on Carrier Materials: A Comprehensive Review
There are two major applications of l-asparaginase (L-ASNase): leukemia therapy and the
food industry. Especially, its chemotherapeutic effect has attracted interest from the scientific …
food industry. Especially, its chemotherapeutic effect has attracted interest from the scientific …
Critical overview of the main features and techniques used for the evaluation of the clinical applicability of L-asparaginase as a biopharmaceutical to treat blood …
TA Costa-Silva, IM Costa, HP Biasoto, GM Lima… - Blood Reviews, 2020 - Elsevier
L-asparaginase is an enzyme used as a biopharmaceutical to treat acute lymphoblastic
leukemia. Several adverse effects have been related to L-asparaginase use, so the scientific …
leukemia. Several adverse effects have been related to L-asparaginase use, so the scientific …
Immobilization of L-asparaginase on magnetic nanoparticles for cancer treatment
H Orhan, D Aktaş Uygun - Applied biochemistry and biotechnology, 2020 - Springer
In this presented work, magnetic poly (HEMA-GMA) nanoparticles were synthesized,
characterized, and used for immobilization of an anti-leukemic enzyme L-asparaginase. The …
characterized, and used for immobilization of an anti-leukemic enzyme L-asparaginase. The …
[HTML][HTML] l-asparaginase immobilized p (HEMA-GMA) cryogels: A recent study for biochemical, thermodynamic and kinetic parameters
Cryogels have recently been attracted intense attention as suitable carriers for enzyme
immobilization. Herein, l-asparaginase was selected as the model enzyme due to its …
immobilization. Herein, l-asparaginase was selected as the model enzyme due to its …
Expression and characterization of recombinant l-asparaginase from Pseudomonas fluorescens
R Sindhu, HK Manonmani - Protein expression and purification, 2018 - Elsevier
Abstract l-asparaginase (EC 3.5. 1.1), an anti-cancer drug has been used in the treatment of
acute lymphoblastic leukemia. A novel source of l-asparaginase from Pseudomonas …
acute lymphoblastic leukemia. A novel source of l-asparaginase from Pseudomonas …
Anticancer, antioxidant activities, and DNA affinity of novel monocationic bithiophenes and analogues
A series of 15 monocationic bithiophenes and isosteres were prepared and subjected to in
vitro antiproliferative screening using the full National Cancer Institute (NCI)-60 cell line …
vitro antiproliferative screening using the full National Cancer Institute (NCI)-60 cell line …
Cloning and expression of l-asparaginase from E. coli in eukaryotic expression system
S Sajitha, J Vidya, P Binod, A Pandey - Biochemical engineering journal, 2015 - Elsevier
Abstract l-Asparaginase is an anti-cancer agent which prevents the proliferation of
cancerous cells by decreasing the level of asparagine in the blood. l-asparaginase from …
cancerous cells by decreasing the level of asparagine in the blood. l-asparaginase from …
Synthesis and characterization of PMMA composites activated with starch for immobilization of L‐asparaginase
ABSTRACT Poly (methyl methacrylate)(PMMA)–starch composites were prepared by
emulsion polymerization technique for L‐asparaginase (L‐ASNase) immobilization as …
emulsion polymerization technique for L‐asparaginase (L‐ASNase) immobilization as …
Biochemical Characterization of $\small {L} $-Asparaginase in NaCl-Tolerant Staphylococcus sp. OJ82 Isolated from Fermented Seafood
Abstract $\small {L} $-Asparaginase from gram-positive bacteria has been poorly explored.
We conducted recombinant overexpression and purification of $\small {L} $-asparaginase …
We conducted recombinant overexpression and purification of $\small {L} $-asparaginase …
[HTML][HTML] Anticancer activity of extremely effective recombinant L-asparaginase from Burkholderia pseudomallei
DB Darwesh, YS Al-Awthan, I Elfaki… - … of Microbiology and …, 2022 - ncbi.nlm.nih.gov
Abstract L-asparaginase (EC 3.5. 1.1) purified from bacterial cells is widely used in the food
industry, as well as in the treatment of childhood acute lymphoblastic leukemia. In the …
industry, as well as in the treatment of childhood acute lymphoblastic leukemia. In the …