HOTAIR LncRNA: a novel oncogenic propellant in human cancer

T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …

Exploring lncRNA-mediated regulatory networks in endometrial cancer cells and the tumor microenvironment: advances and challenges

P Dong, Y Xiong, J Yue, S JB Hanley, N Kobayashi… - Cancers, 2019 - mdpi.com
Recent studies have revealed both the promise and challenges of targeting long non-coding
RNAs (lncRNAs) to diagnose and treat endometrial cancer (EC). LncRNAs are upregulated …

[HTML][HTML] Long non-coding RNAs and endometrial cancer

H Liu, J Wan, J Chu - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Endometrial cancer (EC) is one of the most common gynecologic malignancies. In spite of
the advance in chemotherapy, radiotherapy or surgical techniques for EC in recent years …

Long noncoding RNA HOTAIR mediates the estrogen-induced metastasis of endometrial cancer cells via the miR-646/NPM1 axis

Y Zhou, C Wang, L Mao, Y Wang… - … of Physiology-Cell …, 2018 - journals.physiology.org
LncRNA homeobox (HOX) transcript antisense intergenic RNA (HOTAIR) has been
confirmed to be involved in the tumorigenic progression of endometrial carcinoma (EC) …

The contrary functions of lnc RNA HOTAIR/miR‐17‐5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells

J Jia, D Zhan, J Li, Z Li, H Li… - Journal of cellular and …, 2019 - Wiley Online Library
This study was implemented to figure out whether lnc RNA HOTAIR/miR‐17‐5p/PTEN axis
played a role that was opposite to Shenqifuzheng (SQFZ) injection in regulating the …

[HTML][HTML] Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO

P Yang, T Chen, Z Xu, H Zhu, J Wang, Z He - Oncotarget, 2016 - ncbi.nlm.nih.gov
This study aimed to investigate the role of long noncoding RNAs (lncRNAs) in the metastasis
of colorectal cancer (CRC). Metastasis is an important prognostic factor of CRC, and …

The regulatory roles of lncRNAs in the process of breast cancer invasion and metastasis

S Zhou, Y He, S Yang, J Hu, Q Zhang, W Chen… - Bioscience …, 2018 - portlandpress.com
Breast cancer (BC) is the most common cancer and principal cause of death among females
worldwide. Invasion and metastasis are major causes which influence the survival and …

[HTML][HTML] The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors

H Hardin, R Zhang, H Helein, D Buehler, Z Guo… - Laboratory …, 2017 - Elsevier
The cancer stem-like cell (CSC) hypothesis postulates that a small population of cells in a
cancer has self-renewal and clonal tumor initiation properties. These cells are responsible …

lncRNA OIP5‐AS1 suppresses cell proliferation and invasion of endometrial cancer by regulating PTEN/AKT via sponging miR‐200c‐3p

Y Liu, X Cai, Y Cai, Y Chang - Journal of Immunology Research, 2021 - Wiley Online Library
Background. Endometrial carcinoma (EC) is one of the major gynecologic malignancy
cancers affecting females with dismal prognosis and high mortality around the world …

Long noncoding RNA HOTAIR promotes endometrial carcinoma cell proliferation by binding to PTEN via the activating phosphatidylinositol 3-kinase/Akt signaling …

XH Zhang, P Hu, YQ Xie, YJ Kang… - Molecular and cellular …, 2019 - Am Soc Microbiol
Accumulating evidence has demonstrated that long noncoding RNAs (lncRNAs) exert
essential biological functions in modulating the progression of endometrial carcinoma (EC) …