Metal ions and metal complexes with organic molecules are ubiquitous in nature. Bulk metal
ions of Na, K, Mg, and Ca constitute as much as 1% of human body weight. The remaining …

The biomedical application of discrete supramolecular metal-based structures, including
supramolecular coordination complexes (SCCs), is still an emergent field of study. However …

Self-assembly of ligand 1 and Pd (NO3) 2 delivers Fujita-type metal–organic polyhedron
(MOP) 3 which bears 24 covalently attached methyl viologen units on its external surface, as …

The incorporation of metal ions into nucleic acids by means of metal‐mediated base pairs
represents a promising and prominent strategy for the site‐specific decoration of these self …

The four natural DNA bases (A, T, G and C) associate in base pairs (A= T and G≡ C),
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …

Transition metal complexes offer great potential as diagnostic and therapeutic agents, and a
growing number of biological applications have been explored. To be effective, these …

The helicates—chiral assemblies of two or more metal atoms linked by short or relatively
rigid multidentate organic ligands—may be regarded as non-peptide mimetics of α-helices …

The synthesis of self-assembled metallosupramolecular architectures has been of steadily
growing interest in recent years due to their diverse applications. Appending additional …

Small cationic amphiphilic α-helical peptides are emerging as agents for the treatment of
cancer and infection, but they are costly and display unfavourable pharmacokinetics. Helical …

DNA has been a key target for cancer therapy, with a range of compounds able to bind and
either impair its processing or induce damage. Targeting DNA with small molecules in a truly …