Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections
SJ Hurwitz, R De, JC LeCher, JA Downs-Bowen… - Viruses, 2024 - mdpi.com
Most repurposed drugs have proved ineffective for treating COVID-19. We evaluated median
effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical …
effective and toxic concentrations (EC50, CC50) of 49 drugs, mostly from previous clinical …
1-Sulfonyl-3-amino-1H-1,2,4-triazoles as Yellow Fever Virus Inhibitors: Synthesis and Structure–Activity Relationship
E Kazakova, TR Lane, T Jones, AC Puhl, O Riabova… - ACS …, 2023 - ACS Publications
Yellow fever virus (YFV) transmitted by infected mosquitoes causes an acute viral disease
for which there are no approved small-molecule therapeutics. Our recently developed …
for which there are no approved small-molecule therapeutics. Our recently developed …