The Mechanisms of Disease Caused by Acinetobacter baumannii

FC Morris, C Dexter, X Kostoulias, MI Uddin… - Frontiers in …, 2019 - frontiersin.org
Acinetobacter baumannii is a Gram negative opportunistic pathogen that has demonstrated
a significant insurgence in the prevalence of infections over recent decades. With only a …

Acinetobacter baumannii biofilms: effects of physicochemical factors, virulence, antibiotic resistance determinants, gene regulation, and future antimicrobial treatments

EC Eze, HY Chenia, ME El Zowalaty - Infection and drug …, 2018 - Taylor & Francis
Acinetobacter baumannii is a leading cause of nosocomial infections due to its increased
antibiotic resistance and virulence. The ability of A. baumannii to form biofilms contributes to …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii

L Dijkshoorn, A Nemec, H Seifert - Nature reviews microbiology, 2007 - nature.com
Since the 1970s, the spread of multidrug-resistant (MDR) Acinetobacter strains among
critically ill, hospitalized patients, and subsequent epidemics, have become an increasing …

Global Challenge of Multidrug-Resistant Acinetobacter baumannii

F Perez, AM Hujer, KM Hujer, BK Decker… - Antimicrobial agents …, 2007 - Am Soc Microbiol
We may soon be facing the end of the “antibiotic era.” The initial and seemingly unstoppable
success of antibiotics, the fruit of human ingenuity, has been countered by an escalation of …

Acinetobacter infection – an emerging threat to human health

P Visca, H Seifert, KJ Towner - IUBMB life, 2011 - Wiley Online Library
The genus Acinetobacter comprises a complex and heterogeneous group of bacteria, many
of which are capable of causing a range of opportunistic, often catheter‐related, infections in …

The pgaABCD Locus of Acinetobacter baumannii Encodes the Production of Poly-β-1-6-N-Acetylglucosamine, Which Is Critical for Biofilm Formation

AHK Choi, L Slamti, FY Avci, GB Pier… - Journal of …, 2009 - Am Soc Microbiol
We found that Acinetobacter baumannii contains a pgaABCD locus that encodes proteins
that synthesize cell-associated poly-β-(1-6)-N-acetylglucosamine (PNAG). Both a mutant …

Community-acquired Acinetobacter baumannii: clinical characteristics, epidemiology and pathogenesis

C Dexter, GL Murray, IT Paulsen… - Expert review of anti …, 2015 - Taylor & Francis
Community-acquired Acinetobacter baumannii (CA-Ab) is a rare but serious cause of
community-acquired pneumonia in tropical regions of the world. CA-Ab infections …

Treatment of Multidrug-Resistant Acinetobacter baumannii Ventilator-Associated Pneumonia (VAP) with Intravenous Colistin: A Comparison with Imipenem …

J Garnacho-Montero, C Ortiz-Leyba… - Clinical Infectious …, 2003 - academic.oup.com
We prospectively evaluated the efficacy and toxicity of intravenously administered colistin in
35 episodes of ventilator-associated pneumonia (VAP) due to multidrug-resistant …

[HTML][HTML] Nosocomial bacteremia due to Acinetobacter baumannii: epidemiology, clinical features and treatment

JM Cisneros, J Rodríguez-Baño - Clinical microbiology and infection, 2002 - Elsevier
Acinetobacter baumannii is an important cause of nosocomial infections in many hospitals. It
is difficult to control and infection caused is difficult to treat due to its high resistance in the …