The use of microbial modifying therapies to prevent psoriasis exacerbation and associated cardiovascular comorbidity

E Reali, C Caliceti, A Lorenzini, P Rizzo - Inflammation, 2024 - Springer
Psoriasis has emerged as a systemic disease characterized by skin and joint manifestations
as well as systemic inflammation and cardiovascular comorbidities. Many progresses have …

From the Skin to Distant Sites: T Cells in Psoriatic Disease

E Reali, D Ferrari - International Journal of Molecular Sciences, 2023 - mdpi.com
Human skin has long been known as a protective organ, acting as a mechanical barrier
towards the external environment. More recent is the acquisition that in addition to this …

Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis

L Chi, C Liu, I Gribonika, J Gschwend, D Corral, SJ Han… - Science, 2024 - science.org
Males and females exhibit profound differences in immune responses and disease
susceptibility. However, the factors responsible for sex differences in tissue immunity remain …

Dendritic cells and antigen-specific immunotherapy in autoimmune rheumatic diseases

B Cai, R Thomas - Best Practice & Research Clinical Rheumatology, 2024 - Elsevier
Dendritic cells (DCs) are professional antigen-presenting cells and trigger downstream
immune responses to antigen while integrating cellular pathogen and damage-associated …

[HTML][HTML] Clec12A, CD301b, and FcγRIIB/III define the heterogeneity of murine DC2s and DC3s

L Amon, A Seichter, D Vurnek, L Heger, L Lächele… - Cell Reports, 2024 - cell.com
Over the last decade, multiple studies have investigated the heterogeneity of murine
conventional dendritic cells type 2 (cDC2s). However, their phenotypic similarity with …

Antimicrobial Peptides (AMPs) and the Microbiome in Preterm Infants: Consequences and Opportunities for Future Therapeutics

J Marissen, L Reichert, C Härtel, MI Fortmann… - International Journal of …, 2024 - mdpi.com
Antimicrobial peptides (AMPs) are crucial components of the innate immune system in
various organisms, including humans. Beyond their direct antimicrobial effects, AMPs play …

[HTML][HTML] Commensal myeloid crosstalk in neonatal skin regulates long-term cutaneous type 17 inflammation

MO Dhariwala, AM DeRogatis, JN Okoro, A Weckel… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Early life microbe-immune interactions at barrier surfaces have lasting impacts on the
trajectory towards health versus disease. Monocytes, macrophages and dendritic cells are …

Immune cell trafficking: a novel perspective on the gut-skin axis

J Zhang, Z Yao - Inflammation and Regeneration, 2024 - Springer
Immune cell trafficking, an essential mechanism for maintaining immunological homeostasis
and mounting effective responses to infections, operates under a stringent regulatory …

[图书][B] Advances in immunology

FW Alt - 2004 - books.google.com
Advances in Immunology presents current developments as well as comprehensive reviews
in immunology. Articles address the wide range of topics that comprise immunology …

Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation

PC Cook, SL Brown, EL Houlder, S Baker… - bioRxiv, 2023 - biorxiv.org
Fungal spores are abundant in the environment and a major cause of asthma. Originally
characterised as a type 2 inflammatory disease, allergic airway inflammation that underpins …