Translation of survival benefits observed in glioblastoma clinical trials to populations and to
longer-term survival remains uncertain. We aimed to assess if≥ 2-year survival has …

Background Optimal extent of surgical resection (EOR) of high-grade gliomas (HGGs)
remains uncertain in the elderly given the unclear benefits and potentially higher rates of …

Background Glioblastoma is associated with a poor prognosis in the elderly. Survival has
been shown to increase among patients 70 years of age or younger when temozolomide …

Background Radiotherapy is the standard care in elderly patients with malignant
astrocytoma and the role of primary chemotherapy is poorly defined. We did a randomised …

Purpose The optimal radiotherapy regimen for elderly and/or frail patients with newly
diagnosed glioblastoma remains to be established. This study compared two radiotherapy …

BACKGROUND: Survival after a glioblastoma multiforme (GBM) diagnosis remained static
during the several decades before 1999. We hypothesized that the progressive increase in …

Glioblastoma is the most common and most aggressive form of primary brain tumor in adults
and contributes to high social and medical burden as a result of its incurable nature and …

Object As the population ages, the incidence of glioblastoma multiforme (GBM) among older
patients (age> 65 years) will increase. Older patients, unlike their younger counterparts, are …

Glioblastoma multiforme is the most common primary malignant tumor of the central nervous
system. Despite new insights into glioblastoma pathophysiology, the prognosis for patients …

Background We assessed population-level changes in glioblastoma survival between 2000
and 2013 in Finland, with focus on elderly patients (> 70 y) in order to assess if changes in …