Background Drug-resistant pulmonary tuberculosis (DR-TB) is a significant public health
issue that considerably deters the ongoing TB control efforts in India. The purpose of this …

Rapid and accurate diagnosis of tuberculosis (TB) is essential to control the disease. The
conventional microbiological tests have limitations and there is an urgent need to devise a …

Background Bioaerosols from pulmonary tuberculosis (PTB) patients are a quantitative
predictor of transmission. Current methods involve sophisticated instruments and time …

We developed a novel indirect sandwich immuno–polymerase chain reaction (I-PCR) assay
for the detection of mycobacterial antigen 85B (Ag85B, 30 kDa, Rv1886c) in pulmonary …

Aim: There is controversy regarding the potential fitness costs of rifampicin (RIF) resistance-
conferring mutations in the Mycobacterium tuberculosis (Mtb) rpoB gene. We characterized …

Genital tuberculosis (GTB) is an important cause of infertility in India. Lack of an accurate
diagnostic test has led to an indiscriminate use of antitubercular treatment in infertile women …

Attempts were made to enhance the sensitivity of immuno-PCR assay based on the
detection of cocktail of mycobacterial antigen 85B (Rv1886c), ESAT-6 (Rv3875) and cord …

Background Several nucleic acid amplification techniques (IS6110, 16S rRNA, and 85B
mRNA) were developed for the rapid, direct detection of Mycobacterium tuberculosis. We …

Mycobacterium tuberculosis secreted proteins in culture filtrate and early phase of infection,
such as early secretory antigen target 6 (ESAT-6), culture filtrate protein 10 (CFP-10), and …

Bovine tuberculosis (bTB) has a complex epidemiology and a wide range of host species.
United Kingdom and Ireland are one of the examples where control of bovine tuberculosis …