Significant research and preclinical investment in cancer nanomedicine has produced
several products, which have improved cancer care. Nevertheless, there exists a perception …

Reports of the increasing incidence of male infertility paired with decreasing semen quality
have triggered studies on the effects of lifestyle and environmental factors on the male …

Elevated ambient temperatures affect animal production and welfare. Animal's reduced
production performances during heat stress were traditionally thought to result from the …

In recent years there has been enormous interest in researching oxidative stress. Reactive
oxygen species (ROS) are derived from the metabolism of oxygen as by-products of cell …

Metastatic progression of cancer is associated with poor outcome, and here we examine
metabolic changes underlying this process. Although aerobic glycolysis is known to promote …

Simple Summary Hypoxia is a common feature of solid tumors and associated with poor
outcome in most cancer types and treatment modalities, including radiotherapy …

Simple Summary The term hypoxia is used to describe biological situations where
insufficient levels of oxygen exist. Hypoxia and hypoxic states can occur in a range of …

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …

Cancer cells exhibit a wide range of metabolic phenotypes, ranging from strict aerobic
glycolysis to increased mitochondrial respiration. The cause and utility of this metabolic …

Hyperthermia, though by itself generally non-curative for cancer, can significantly increase
the efficacy of radiation therapy, as demonstrated by in vitro, in vivo, and clinical results. Its …