Targeting cancer metabolic pathways for improving chemotherapy and immunotherapy

Z Luo, KM Eichinger, A Zhang, S Li - Cancer letters, 2023 - Elsevier
Recent discoveries in cancer metabolism have revealed promising metabolic targets to
modulate cancer progression, drug response, and anti-cancer immunity. Combination …

Focus on the molecular mechanisms of cisplatin resistance based on multi-omics approaches

P Yue, B Han, Y Zhao - Molecular Omics, 2023 - pubs.rsc.org
Cisplatin is commonly used in combination with other cytotoxic agents as a standard
treatment regimen for a variety of solid tumors, such as lung, ovarian, testicular, and head …

Flexible Organic Photovoltaic‐Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds

YW Hu, YH Wang, F Yang, DX Liu, GH Lu… - Advanced …, 2024 - Wiley Online Library
Electrical stimulation (ES) is proposed as a therapeutic solution for managing chronic
wounds. However, its widespread clinical adoption is limited by the requirement of …

Structural N-glycoproteomics characterization of cell-surface N-glycosylation of MCF-7/ADR cancer stem cells

H Yang, F Xu, Y Chen, Z Tian - Journal of Chromatography B, 2023 - Elsevier
Breast cancer is responsible for the highest mortality all over the world. Cancer stem cells
(CSCs) along with epithelial mesenchymal transition (EMT) are identified as a driver of …

A brief review on chemoresistance; targeting cancer stem cells as an alternative approach

B Toledo, A González-Titos… - International Journal of …, 2023 - mdpi.com
The acquisition of resistance to traditional chemotherapy and the chemoresistant metastatic
relapse of minimal residual disease both play a key role in the treatment failure and poor …

Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway

W Song, C Liang, Y Sun, S Morii, S Yomogida… - Journal of Biological …, 2023 - ASBMB
The phenomenon of multidrug resistance (MDR) is called chemoresistance with respect to
the treatment of cancer, and it continues to be a major challenge. The role of N-glycosylation …

Advances in the application of proteomics in lung cancer

B Ling, Z Zhang, Z Xiang, Y Cai, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Although the incidence and mortality of lung cancer have decreased significantly in the past
decade, it is still one of the leading causes of death, which greatly impairs people's life and …

Clinical glycoproteomics: methods and diseases

Y Wang, K Lei, L Zhao, Y Zhang - MedComm, 2024 - Wiley Online Library
Glycoproteins, representing a significant proportion of posttranslational products, play
pivotal roles in various biological processes, such as signal transduction and immune …

High Antimicrobial Electrotherapy and Wound Monitoring Hydrogel with Bimetal Phenolic Networks for Smart Healthcare

Q Yang, R Chen, M Li, H Song, X Zhao… - Advanced Functional …, 2024 - Wiley Online Library
The design and fabrication of novel soft bioelectronic materials for rapid wound healing and
real‐time monitoring are critical for smart healthcare. However, developing such integrated …

TFEB controls sensitivity to chemotherapy and immuno-killing in non-small cell lung cancer

M Akman, C Monteleone, G Doronzo, M Godel… - Journal of Experimental …, 2024 - Springer
Background In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is
affected by the high expression of drug efflux transporters as ABCC1 and by the low …