The skin, being the barrier organ of the body, is constitutively exposed to various stimuli
impacting its morphology and function. Senescent cells have been found to accumulate with …

Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …

In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas
LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here …

Hybridization is widely recognized as promoting both species and phenotypic diversity.
However, its role in mammalian evolution is rarely examined. We report historical …

Melanins are widely distributed in animals and plants; in vertebrates, most melanins are
present on the body surface. The diversity of pigmentation in vertebrates is mainly attributed …

Skin cancers are among the most common cancers worldwide and are increasingly
prevalent. Cutaneous melanoma (CM) is characterized by the malignant transformation of …

Melanocytes, which originate from the neuroectoderm, are specialized cells responsible for
producing pigments and possessing a dendritic morphology. These cells migrate to the …

Copper is vital for numerous cellular functions affecting all tissues and organ systems in the
body. The copper pump, ATP7A is critical for whole-body, cellular, and subcellular copper …

Body colour is an important economic trait for commercial fishes. Recently, a new colour
morph displaying market-favoured yellow skin (termed as yellow-mutant, YM) of northern …

Post-inflammatory hypopigmentation is a common acquired pigmentary disorder that is more
prominent in skin of color, leading to great cosmetic and psychosocial implications. Often, a …