The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain

A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

Cellular, molecular, and clinical mechanisms of action of deep brain stimulation—a systematic review on established indications and outlook on future developments

M Jakobs, A Fomenko, AM Lozano… - EMBO molecular …, 2019 - embopress.org
Deep brain stimulation (DBS) has been successfully used to treat movement disorders, such
as Parkinson's disease, for more than 25 years and heralded the advent of electrical …

Network perspectives on the mechanisms of deep brain stimulation

CC McIntyre, PJ Hahn - Neurobiology of disease, 2010 - Elsevier
Deep brain stimulation (DBS) is an established medical therapy for the treatment of
movement disorders and shows great promise for several other neurological disorders …

Therapeutic deep brain stimulation in Parkinsonian rats directly influences motor cortex

Q Li, Y Ke, DCW Chan, ZM Qian, KKL Yung, H Ko… - Neuron, 2012 - cell.com
Much recent discussion about the origin of Parkinsonian symptoms has centered around the
idea that they arise with the increase of beta frequency waves in the EEG. This activity may …

Critical review—approaches for the electrochemical interrogation of DNA-based sensors: a critical review

MA Pellitero, A Shaver… - Journal of The …, 2019 - iopscience.iop.org
The desire to improve and decentralize diagnostic platforms to facilitate highly precise and
personalized medicine has motivated the development of a large number of electrochemical …

Computational analysis of subthalamic nucleus and lenticular fasciculus activation during therapeutic deep brain stimulation

S Miocinovic, M Parent, CR Butson… - Journal of …, 2006 - journals.physiology.org
The subthalamic nucleus (STN) is the most common target for the treatment of Parkinson's
disease (PD) with deep brain stimulation (DBS). DBS of the globus pallidus internus (GPi) is …

Patient-specific models of deep brain stimulation: influence of field model complexity on neural activation predictions

A Chaturvedi, CR Butson, SF Lempka, SE Cooper… - Brain stimulation, 2010 - Elsevier
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become the surgical
therapy of choice for medically intractable Parkinson's disease. However, quantitative …

Acetylcholine–dopamine interactions in the pathophysiology and treatment of CNS disorders

DB Lester, TD Rogers, CD Blaha - CNS neuroscience & …, 2010 - Wiley Online Library
Dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area of
the midbrain form the nigrostriatal and mesocorticolimbic dopaminergic pathways that …

[HTML][HTML] Mechanisms and targets of deep brain stimulation in movement disorders

MD Johnson, S Miocinovic, CC McIntyre, JL Vitek - Neurotherapeutics, 2008 - Elsevier
Chronic electrical stimulation of the brain, known as deep brain stimulation (DBS), has
become a preferred surgical treatment for medication-refractory movement disorders …

Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation

S Li, GW Arbuthnott, MJ Jutras… - Journal of …, 2007 - journals.physiology.org
Deep brain stimulation (DBS) is an effective treatment of Parkinson's disease (PD) for many
patients. The most effective stimulation consists of high-frequency biphasic stimulation …