[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

[HTML][HTML] Development of prefrontal cortex

SM Kolk, P Rakic - Neuropsychopharmacology, 2022 - nature.com
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function

AL Garcia-Garcia, A Newman-Tancredi… - …, 2014 - Springer
Abstract Rationale Serotonin (5-HT) neurotransmission is intimately linked to anxiety and
depression and a diverse body of evidence supports the involvement of the main inhibitory …

The serotonergic system in fish

C Lillesaar - Journal of chemical neuroanatomy, 2011 - Elsevier
Abstract Neurons using serotonin (5-HT) as neurotransmitter and/or modulator have been
identified in the central nervous system in representatives from all vertebrate clades …

[HTML][HTML] Developmental origins of brain disorders: roles for dopamine

KM Money, GD Stanwood - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Neurotransmitters and neuromodulators, such as dopamine, participate in a wide range of
behavioral and cognitive functions in the adult brain, including movement, cognition, and …

Probing the diversity of serotonin neurons

P Gaspar, C Lillesaar - … of the Royal Society B: Biological …, 2012 - royalsocietypublishing.org
The serotonin (5-HT) system is generally considered as a single modulatory system, with
broad and diffuse projections. However, accumulating evidence points to the existence of …

Important role of mucosal serotonin in colonic propulsion and peristaltic reflexes: in vitro analyses in mice lacking tryptophan hydroxylase 1

DJ Heredia, MD Gershon, SD Koh… - The Journal of …, 2013 - Wiley Online Library
Key points• Previous studies have indicated that neither neuronal nor mucosal 5‐
hydroxytryptamine (5‐HT) are important for colonic migrating motor complexes (CMMCs) or …

Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity

M Angoa‐Pérez, MJ Kane, DI Briggs… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 121, 974–984. Abstract Neuropsychiatric disorders characterized by
behavioral disinhibition, including disorders of compulsivity (eg obsessive–compulsive …

Rethinking 5-HT1A Receptors: Emerging Modes of Inhibitory Feedback of Relevance to Emotion-Related Behavior

SC Altieri, AL Garcia-Garcia, ED Leonardo… - ACS chemical …, 2013 - ACS Publications
The complexities of the involvement of the serotonin transmitter system in numerous
biological processes and psychiatric disorders is, to a substantial degree, attributable to the …

Investigating anxiety and depressive-like phenotypes in genetic mouse models of serotonin depletion

SP Fernandez, P Gaspar - Neuropharmacology, 2012 - Elsevier
Emotional disorders such as depression, panic attacks, generalized anxiety, phobias and
post-traumatic stress have been associated to decreased serotonin (5-HT) function, based …