Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Recent advances in nanoparticle applications in respiratory disorders: a review

ME Taghavizadeh Yazdi, M Qayoomian… - Frontiers in …, 2023 - frontiersin.org
Various nanoparticles are used in the discovery of new nanomedicine to overcome the
shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to …

Role of particle size in translational research of nanomedicines for successful drug delivery: Discrepancies and inadequacies

HW Chan, S Chow, X Zhang, PCL Kwok… - Journal of Pharmaceutical …, 2023 - Elsevier
Despite significant research progress in substantiating the therapeutic merits of
nanomedicines and the emergence of sophisticated nanotechnologies, the translation of this …

Nano-formulations for pulmonary delivery: Past, present, and future perspectives

S Peng, W Wang, R Zhang, C Wu, X Pan, Z Huang - Pharmaceutics, 2024 - mdpi.com
With the development of nanotechnology and confronting the problems of traditional
pharmaceutical formulations in treating lung diseases, inhalable nano-formulations have …

Novel inhalable nano-based/microparticles for enhanced sustained pulmonary delivery of remdesivir-A patient malleable treatment for coronaviruses infection: In vitro …

SA Fouad, FA Malaak, MH Teaima, S Omar… - Journal of Drug Delivery …, 2024 - Elsevier
Remdesivir (RDV) is an antiviral used in potential treatment of SARS-COV-2 infection during
the COVID-19 pandemic worldwide. However, it is still limited to IV administration for …

Supercritical antisolvent-fluidized bed for the preparation of dry powder inhaler for pulmonary delivery of nanomedicine

Z Ma, X Zhang, L Ping, Z Zhong, X Zhang… - International Journal of …, 2023 - Elsevier
The supercritical antisolvent-fluidized bed coating process (SAS-FB) shows great potential
as a technique to manufacture dry powder inhaler (DPI) that incorporate nanodrugs onto …

Nano-based carriers for pulmonary drug delivery: A review on the available drug delivery applications and toxicity issues

PI Siafaka, EÖ Bülbül, AN Miliotou, ID Karantas… - Journal of Drug Delivery …, 2024 - Elsevier
In the last decade, nanocarriers have been widely used to target specific organs and
disorders of any kind. Nonetheless, the commercialization of nanocarriers for many …

[HTML][HTML] Novel administration routes, delivery vectors, and application of vaccines based on biotechnologies: a review

CI Rai, TH Kuo, YC Chen - Vaccines, 2024 - mdpi.com
Traditional vaccines can be classified into inactivated vaccines, live attenuated vaccines,
and subunit vaccines given orally or via intramuscular (IM) injection or subcutaneous (SC) …

Lipid polymer hybrid nanoparticles against lung cancer and their application as inhalable formulation

SN Kassaee, D Richard, GA Ayoko, N Islam - Nanomedicine, 2024 - Taylor & Francis
Lung cancer is a leading cause of global cancer mortality, often treated with
chemotherapeutic agents. However, conventional approaches such as oral or intravenous …

[HTML][HTML] Nanoparticle-based drug delivery systems in inhaled therapy: improving respiratory medicine

E Cojocaru, OR Petriș, C Cojocaru - Pharmaceuticals, 2024 - mdpi.com
Inhaled nanoparticle (NP) therapy poses intricate challenges in clinical and
pharmacodynamic realms. Recent strides have revolutionized NP technology by enabling …