Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and …

Y Zhao, L Bai, Y Zhang, R Yao, Y Sun, R Hang, X Chen… - Biomaterials, 2022 - Elsevier
Osseointegration of implants is a complex physiological process that requires temporal and
spatial regulation of immune responses, angiogenesis, and osteogenesis. To achieve …

Porcine model for the study of sperm capacitation, fertilization and male fertility

M Zigo, P Maňásková-Postlerová, D Zuidema… - Cell and tissue …, 2020 - Springer
Mammalian fertilization remains a poorly understood event with the vast majority of studies
done in the mouse model. The purpose of this review is to revise the current knowledge …

Proteomic analysis of extracellular vesicles secreted by primary human epithelial endometrial cells reveals key proteins related to embryo implantation

M Segura-Benítez, MC Carbajo-García… - Reproductive Biology …, 2022 - Springer
Background Successful implantation is dependent on coordination between maternal
endometrium and embryo, and the role of EVs in the required cross-talk cell-to-cell has been …

Identification of potential key genes related to idiopathic male infertility using RNA-sequencing data: an in-silico approach

LK Lukkani, LD Naorem, M Muthaiyan… - Human …, 2023 - Taylor & Francis
Among reproductive health problems, idiopathic infertility affects married couples. The
current diagnosis of male infertility focuses on the concentration, motility, and morphology of …

Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation

C Ma, X Wang, S He, L Zhang, J Bai, L Qu, J Qi… - Cell & Bioscience, 2022 - Springer
Background Excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) is
the main cause of hypoxic pulmonary hypertension (PH), and mitochondrial homeostasis …

Immune responses of different COVID-19 vaccination strategies by analyzing single-cell RNA sequencing data from multiple tissues using machine learning methods

H Li, Q Ma, J Ren, W Guo, K Feng, Z Li, T Huang… - Frontiers in …, 2023 - frontiersin.org
Multiple types of COVID-19 vaccines have been shown to be highly effective in preventing
SARS-CoV-2 infection and in reducing post-infection symptoms. Almost all of these vaccines …

[HTML][HTML] Degradation of CCNB1 mediated by APC11 through UBA52 ubiquitination promotes cell cycle progression and proliferation of non-small cell lung cancer …

F Wang, X Chen, X Yu, Q Lin - American journal of translational …, 2019 - ncbi.nlm.nih.gov
Objective: Mechanism by which CCNB1 regulates the cell cycle progression and its
prognostic function in non-squamous non-small cell lung cancer (NSCLC) are necessary to …

Single‐cell transcriptome analysis of human oocyte ageing

L Yuan, P Yin, H Yan, X Zhong, C Ren… - Journal of Cellular …, 2021 - Wiley Online Library
Oocyte ageing is a key bottleneck and intractable challenge for in vitro fertilization treatment
of aged female patients. The underlying molecular mechanisms of human oocyte ageing …

High-throughput sequencing reveals hub genes for human early embryonic development arrest in vitro fertilization: a pilot study

W Zhang, K Li, S Li, R Lv, J Ma, P Yin, L Li… - Frontiers in …, 2023 - frontiersin.org
Many clinical studies have shown that embryos of in vitro fertilization (IVF) are often prone to
developmental arrest, which leads to recurrent failure of IVF treatment. Early embryonic …

Multiple myeloma: bioinformatic analysis for identification of key genes and pathways

C Saadoune, B Nouadi, H Hamdaoui… - … and Biology Insights, 2022 - journals.sagepub.com
Multiple myeloma (MM) is a hematological malignancy in which monoclonal plasma cells
multiply in the bone marrow and monoclonal immunoglobulins are overproduced in older …