Synthesis and application of coumarin fluorescence probes

X Sun, T Liu, J Sun, X Wang - RSC advances, 2020 - pubs.rsc.org
In recent years, the research on fluorescent probes has developed rapidly. Coumarin
fluorescent probes have also been one of the hot topics in recent years. For the synthesis …

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

MOF-818 nanozyme-based colorimetric and electrochemical dual-mode smartphone sensing platform for in situ detection of H2O2 and H2S released from living cells

K Yu, M Li, H Chai, Q Liu, X Hai, M Tian, L Qu… - Chemical Engineering …, 2023 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2) and hydrogen sulfide (H 2 S) play a key role in many
cellular signaling pathways. The efficient and accurate in situ detection of H 2 O 2 and H 2 S …

[HTML][HTML] Hydrogen sulfide signaling in mitochondria and disease

B Murphy, R Bhattacharya, P Mukherjee - The FASEB Journal, 2019 - ncbi.nlm.nih.gov
Hydrogen sulfide can signal through 3 distinct mechanisms: 1) reduction and/or direct
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …

Hydrogen sulfide: its production, release and functions

H Kimura - Amino acids, 2011 - Springer
Abstract Hydrogen sulfide (H 2 S), which is a well-known toxic gas, has been recognized as
a signal molecule as well as a cytoprotectant. It is produced by three enzymes, cystathionine …

The Slow-Releasing Hydrogen Sulfide Donor, GYY4137, Exhibits Novel Anti-Cancer Effects In Vitro and In Vivo

ZW Lee, J Zhou, CS Chen, Y Zhao, CH Tan, L Li… - PloS one, 2011 - journals.plos.org
The slow-releasing hydrogen sulfide (H2S) donor, GYY4137, caused concentration-
dependent killing of seven different human cancer cell lines (HeLa, HCT-116, Hep G2, HL …

AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of …

B Szczesny, K Módis, K Yanagi, C Coletta… - Nitric oxide, 2014 - Elsevier
The purpose of the current study was to investigate the effect of the recently synthesized
mitochondrially-targeted H 2 S donor, AP39 [(10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5yl) …

Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models

LF Hu, M Lu, CX Tiong, GS Dawe, G Hu, JS Bian - Aging cell, 2010 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder characterized by a progressive
loss of dopaminergic neurons in the substantia nigra (SN). The present study was designed …

Antioxidant and cell‐signaling functions of hydrogen sulfide in the central nervous system

U Shefa, MS Kim, NY Jeong… - Oxidative medicine and …, 2018 - Wiley Online Library
Hydrogen sulfide (H2S), a toxic gaseous molecule, plays a physiological role in regulating
homeostasis and cell signaling. H2S is produced from cysteine by enzymes, such as …

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

K Suzuki, G Olah, K Modis, C Coletta… - Proceedings of the …, 2011 - National Acad Sciences
The goal of the present studies was to investigate the role of changes in hydrogen sulfide
(H2S) homeostasis in the pathogenesis of hyperglycemic endothelial dysfunction. Exposure …