Tolerance and innate immunity shape the development of postpartum uterine disease and the impact of endometritis in dairy cattle

IM Sheldon, JG Cronin… - Annual review of animal …, 2019 - annualreviews.org
Bacteria are ubiquitous in the bovine uterus after parturition, but 50 years ago, cows
tolerated these bacteria and few animals developed uterine disease. Now, up to 40% of …

[HTML][HTML] Metabolic and immunological changes in transition dairy cows: A review

PR Wankhade, A Manimaran, A Kumaresan… - Veterinary …, 2017 - ncbi.nlm.nih.gov
Smooth transition from pregnancy to lactation is important for high productive and
reproductive performance during later postpartum period in dairy animals. On the other …

Monitoring metabolic health of dairy cattle in the transition period

S LeBlanc - Journal of reproduction and Development, 2010 - jstage.jst.go.jp
This paper reviews the importance of energy metabolism in transition dairy cows, its
associations with disease and reproduction, and strategies for monitoring cows under field …

A review of the ongoing discussion about definition, diagnosis and pathomechanism of subclinical endometritis in dairy cows

K Wagener, C Gabler, M Drillich - Theriogenology, 2017 - Elsevier
In the last decade, several new aspects of the inflammation of the bovine endometrium have
been investigated and described, including a new definition of subclinical endometritis. This …

Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and …

JG Cronin, ML Turner, L Goetze, CE Bryant… - Biology of …, 2012 - academic.oup.com
Infection of the bovine endometrium with Gram-negative bacteria commonly causes uterine
disease. Toll-like receptor 4 (TLR4) on cells of the immune system bind Gram-negative …

Interactions of metabolism, inflammation, and reproductive tract health in the postpartum period in dairy cattle

SJ LeBlanc - Reproduction in Domestic Animals, 2012 - Wiley Online Library
Contents This paper reviews recent data and concepts on the development of inflammation
in the reproductive tract of dairy cows during the first 2 months after calving. The incidence of …

Reproductive tract inflammatory disease in postpartum dairy cows

SJ LeBlanc - Animal, 2014 - cambridge.org
Up to half of dairy cows are affected by at least one of metritis, purulent vaginal discharge,
endometritis or cervicitis in the postpartum period. These conditions result from inadequate …

Mechanisms linking bacterial infections of the bovine endometrium to disease and infertility

LC Carneiro, JG Cronin, IM Sheldon - Reproductive biology, 2016 - Elsevier
Bacterial infections of the endometrium after parturition commonly cause metritis and
endometritis in dairy cattle, and these diseases are important because they compromise …

Reproductive tract defense and disease in postpartum dairy cows

SJ LeBlanc, T Osawa, J Dubuc - Theriogenology, 2011 - Elsevier
This paper briefly reviews recent data and concepts on the development and mitigation of
infection and inflammation in the reproductive tract of dairy cows during the first 2 mo after …

Innate immunity and inflammation of the bovine female reproductive tract in health and disease

IM Sheldon, JG Cronin, GD Healey, C Gabler… - …, 2014 - rep.bioscientifica.com
In mammals, the sperm activates the development of the egg by triggering a series of
oscillations in the cytosolic-free Ca 2+ concentration (Ca 2+ i). The sperm triggers these …