Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Heart failure (HF) is a clinical syndrome that usually develops in the elderly. Complex
interactions of the cardiovascular aging process with risk factors (obesity, hypertension, and …

Fibrotic remodelling of the extracellular matrix is a healing mechanism necessary
immediately after myocardial injury. However, prolonged increase in myocardial fibrotic …

Background Fibroblast activation protein (FAP) as a specific marker of activated fibroblasts
can be visualized by positron emission tomography (PET) using Ga-68-FAP inhibitors …

Myocardial interstitial fibrosis is part of the advanced disease stage of most cardiovascular
pathologies. It has been characterized histologically in various disease settings from …

Abstract Purpose of Review Given that the life expectancy and the burden of hypertension
are projected to increase over the next decade, hypertensive heart disease (HHD) may be …

Background: Coronary artery disease (CAD) remains the major cause of cardiac morbidity
and mortality worldwide, despite the advances in treatment with coronary revascularization …

Background—This study sought to assess cross-sectional associations of aortic stiffness
assessed by magnetic resonance imaging with left ventricular (LV) remodeling and …