New tools for controlling tuberculosis are urgently needed. Despite our emerging
understanding of the biogeography of Mycobacterium tuberculosis, the implications for …

Molecular epidemiologic studies of tuberculosis (TB) have focused largely on utilizing
molecular techniques to address short-and long-term epidemiologic questions, such as in …

Abstract Background The Direct Repeat locus of the Mycobacterium tuberculosis complex
(MTC) is a member of the CRISPR (Clustered regularly interspaced short palindromic …

In a previous report, we described a PCR protocol for the differentiation of the various
species of the Mycobacterium tuberculosis complex (MTC) on the basis of genomic …

Beijing/W strains of Mycobacterium tuberculosis are geographically widespread and
hypervirulent. To enhance our understanding of their origin and evolution, we sought …

Much remains unknown of the phylogeny and evolution of Mycobacterium tuberculosis, an
organism that kills 2 million people annually. Using a population-based approach that …

Tuberculosis is an ever-changing field. The editors and authors of “Tuberculosis 2007–from
basic science to patient care” have made every effort to provide information that is accurate …

Background After the collapse of the Soviet Union, dramatically increasing rates of
tuberculosis and multidrug-resistant tuberculosis (MDR-TB) have been reported from …

Recent genotyping studies of Mycobacterium tuberculosis in Ethiopia have reported the
identification of a new phylogenetically distinct M. tuberculosis lineage, lineage 7. We …

Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique
spoligotype signatures specifically associated with IS 6110-defined strain families …