Massively parallel whole transcriptome sequencing, commonly referred to as RNA-Seq, has
become the technology of choice for performing gene expression profiling. However …

The paper addresses the problem of how to use RNA-Seq data for transcriptome
reconstruction and quantification, as well as novel transcript discovery in partially annotated …

High-throughput RNA sequencing (RNA-Seq) is a popular cost-efficient technology with
many medical and biological applications. This technology, however, presents a number of …

In this paper, we propose a novel, intuitive and flexible approach for transcriptome
reconstruction from single RNA-Seq reads, called “Maximum Likelihood Integer …

Massively parallel whole transcriptome sequencing and its ability to generate full
transcriptome data at the single transcript level provides a powerful tool with multiple …

Next-generation sequencing (NGS) and mass spectrometry technologies bring
unprecedented throughput, scalability and speed, facilitating the studies of biological …

In this work, we propose a novel statistical" genome-guided" method called" Transciptome
Reconstruction us-ing Integer Programing"(TRIP) that incorporates fragment length …