The tumor microenvironment: a milieu hindering and obstructing antitumor immune responses
A Labani-Motlagh, M Ashja-Mahdavi… - Frontiers in …, 2020 - frontiersin.org
The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
NKG2D and its ligands:“one for all, all for one”
The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly
diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal …
diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal …
NKG2D ligands–critical targets for cancer immune escape and therapy
D Schmiedel, O Mandelboim - Frontiers in immunology, 2018 - frontiersin.org
DNA damage, oncogene activation and excessive proliferation, chromatin modulations or
oxidative stress are all important hallmarks of cancer. Interestingly, all of these abnormalities …
oxidative stress are all important hallmarks of cancer. Interestingly, all of these abnormalities …
Placenta‐derived exosomes and syncytiotrophoblast microparticles and their role in human reproduction: immune modulation for pregnancy success
L Mincheva‐Nilsson, V Baranov - American journal of …, 2014 - Wiley Online Library
The syncytiotrophoblast (STB) of human placenta constitutively produces and secretes
extracellular vesicles of different size, morphology and function that enter the maternal …
extracellular vesicles of different size, morphology and function that enter the maternal …
The role of placental exosomes in reproduction
L Mincheva‐Nilsson, V Baranov - American journal of …, 2010 - Wiley Online Library
Citation Mincheva‐Nilsson L, Baranov V. The Role of Placental Exosomes in Reproduction.
Am J Reprod Immunol 2010 Cell communication comprises cell–cell contact, soluble …
Am J Reprod Immunol 2010 Cell communication comprises cell–cell contact, soluble …
Generation of soluble NKG 2 D ligands: proteolytic cleavage, exosome secretion and functional implications
G Chitadze, J Bhat, M Lettau… - Scandinavian journal …, 2013 - Wiley Online Library
The activating natural killer group 2 member D (NKG 2 D) receptor is expressed on NK cells,
cytotoxic T cells and additional T cell subsets. Ligands for human NKG 2 D comprise two …
cytotoxic T cells and additional T cell subsets. Ligands for human NKG 2 D comprise two …
Cytotoxicity of CD56bright NK Cells towards Autologous Activated CD4+ T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A
N Nielsen, N Ødum, B Ursø, LL Lanier, P Spee - PloS one, 2012 - journals.plos.org
In mouse models of chronic inflammatory diseases, Natural Killer (NK) cells can play an
immunoregulatory role by eliminating chronically activated leukocytes. Indirect evidence …
immunoregulatory role by eliminating chronically activated leukocytes. Indirect evidence …
NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes
J Fan, J Shi, Y Zhang, J Liu, C An, H Zhu, P Wu… - The EMBO …, 2022 - embopress.org
Stimulatory immune receptor NKG2D binds diverse ligands to elicit differential anti‐tumor
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …
An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination
Y Bauman, D Nachmani, A Vitenshtein, P Tsukerman… - Cell host & …, 2011 - cell.com
The human polyoma viruses JCV and BKV establish asymptomatic persistent infection in
65%–90% of humans but can cause severe illness under immunosuppressive conditions …
65%–90% of humans but can cause severe illness under immunosuppressive conditions …
Regulation of NKG2D stress ligands and its relevance in cancer progression
AB Jones, A Rocco, LS Lamb, GK Friedman… - Cancers, 2022 - mdpi.com
Simple Summary Immune surveillance during periods of cellular stress is necessary to
maintain homeostasis. In distressed cells, the expression of stress (natural killer group 2 …
maintain homeostasis. In distressed cells, the expression of stress (natural killer group 2 …