Maturity-onset diabetes of the young (MODY) is an unusual form of diabetes with specific
features that distinguish it from type 1 and type 2 diabetes. There are 14 known subtypes of …

Over the last decade, we have witnessed major advances in the understanding of the
molecular basis of neonatal and infancy-onset diabetes. It is now widely accepted that …

Background Traditional genetic testing focusses on analysis of one or a few genes
according to clinical features; this approach is changing as improved sequencing methods …

OBJECTIVE Monogenic diabetes, a young-onset form of diabetes, is often misdiagnosed as
type 1 diabetes, resulting in unnecessary treatment with insulin. A screening approach for …

AIMS: Potassium inwardly rectifier 6.2 subunit (Kir6. 2) of the ATP-sensitive potassium
(KATP) channel encoded by KCNJ11 gene is a therapeutical target for sulfonylureas …

Objective To characterize the initial presentation and clinical course of patients with
hepatocyte nuclear factor (HNF) 4A‒and HNF1B‒MODY in a multinational registry. Design …

Monogenic diabetes is a genetic disorder caused by one or more variations in a single
gene. It encompasses a broad spectrum of heterogeneous conditions, including neonatal …

Objective To describe clinical presentation/longterm outcomes of patients with
ABCC8/KCNJ11 variants in a large cohort of patients with diabetes. Research Design and …

Diabetes Mellitus (DM) is a complex disease with a significant impact in today's world.
Studies have emphasized the crucial role of genetics in DM, unraveling the distinction of …

Abstract Type 2 diabetes (T2D) mellitus is a common complex disease that currently affects
more than 400 million people worldwide and has become a global health problem. High …