Adjuvant chemotherapy with melatonin for targeting human cancers: A review
Melatonin is a multifunctional hormone that has long been known for its antitumoral effects.
An advantage of the application of melatonin in cancer therapy is its ability to differentially …
An advantage of the application of melatonin in cancer therapy is its ability to differentially …
Standard operating procedure to optimize resazurin-based viability assays
J Petiti, L Revel, C Divieto - Biosensors, 2024 - mdpi.com
The resazurin assay, also known as the Alamar Blue assay, stands as a cornerstone
technique in cell biology, microbiology, and drug development. It assesses the viability of …
technique in cell biology, microbiology, and drug development. It assesses the viability of …
[HTML][HTML] Design of nanostructured lipid carriers and solid lipid nanoparticles for enhanced cellular uptake
F Veider, ZB Akkuş-Dağdeviren, P Knoll… - International Journal of …, 2022 - Elsevier
In this study PEG-free and zeta potential changing lipid-based nanocarriers providing
enhanced cellular uptake were developed. Nanostructured lipid carriers (NLC), consisting of …
enhanced cellular uptake were developed. Nanostructured lipid carriers (NLC), consisting of …
Zeta potential changing polyphosphate nanoparticles: a promising approach to overcome the mucus and epithelial barrier
The aim of the present study was to develop zeta potential-changing polyphosphate
nanoparticles (pp-NPs) in order to overcome the diffusion barrier of the mucus gel layer and …
nanoparticles (pp-NPs) in order to overcome the diffusion barrier of the mucus gel layer and …
[HTML][HTML] Encapsulation within a coordination cage modulates the reactivity of redox-active dyes
Confining molecules within well-defined nanosized spaces can profoundly alter their
physicochemical characteristics. For example, the controlled aggregation of chromophores …
physicochemical characteristics. For example, the controlled aggregation of chromophores …
[HTML][HTML] Inhibition of P-glycoprotein-mediated efflux by thiolated cyclodextrins
F Veider, S Haddadzadegan, ES Armengol… - Carbohydrate …, 2024 - Elsevier
Overcoming P-glycoprotein (P-gp)-mediated efflux poses a significant challenge for the
pharmaceutical industry. This study investigates the potential of thiolated β-cyclodextrins (β …
pharmaceutical industry. This study investigates the potential of thiolated β-cyclodextrins (β …
Peptide Antibiotic–Polyphosphate Nanoparticles: A Promising Strategy to Overcome the Enzymatic and Mucus Barrier of the Intestine
A Saleh, ZB Akkuş-Dağdeviren… - …, 2023 - ACS Publications
The aim of this study was to develop peptide antibiotic–polyphosphate nanoparticles that
are able to overcome the enzymatic and mucus barriers providing a targeted drug release …
are able to overcome the enzymatic and mucus barriers providing a targeted drug release …
[HTML][HTML] A multi-purpose approach to the mechanisms of action of two biocides (Benzalkonium chloride and Dibromonitrilopropionamide): discussion of pseudomonas …
Biocides are widely used in water treatment for microbiological control. The rise of
antimicrobial resistance and the need to assure properly managed water systems require a …
antimicrobial resistance and the need to assure properly managed water systems require a …
[HTML][HTML] PEG vs. zwitterions: How these surface decorations determine cellular uptake of lipid-based nanocarriers
D Stengel, BH Demirel, P Knoll, M Truszkowska… - Journal of colloid and …, 2023 - Elsevier
Aim To evaluate the impact of polyethylene glycol (PEG) and zwitterionic surface decoration
of lipid-based nanocarriers (NC) on cellular uptake. Methods Anionic, neutral and cationic …
of lipid-based nanocarriers (NC) on cellular uptake. Methods Anionic, neutral and cationic …
Facile synthesis, pharmacological and In silico analysis of succinimide derivatives: An approach towards drug discovery
J Rasgania, R Gavadia, K Jakhar - Journal of Molecular Structure, 2023 - Elsevier
The hybrid heterocyclic scaffolds possess extensive medicinal values and significant
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …