Melatonin is a multifunctional hormone that has long been known for its antitumoral effects.
An advantage of the application of melatonin in cancer therapy is its ability to differentially …

The resazurin assay, also known as the Alamar Blue assay, stands as a cornerstone
technique in cell biology, microbiology, and drug development. It assesses the viability of …

In this study PEG-free and zeta potential changing lipid-based nanocarriers providing
enhanced cellular uptake were developed. Nanostructured lipid carriers (NLC), consisting of …

The aim of the present study was to develop zeta potential-changing polyphosphate
nanoparticles (pp-NPs) in order to overcome the diffusion barrier of the mucus gel layer and …

Confining molecules within well-defined nanosized spaces can profoundly alter their
physicochemical characteristics. For example, the controlled aggregation of chromophores …

Overcoming P-glycoprotein (P-gp)-mediated efflux poses a significant challenge for the
pharmaceutical industry. This study investigates the potential of thiolated β-cyclodextrins (β …

The aim of this study was to develop peptide antibiotic–polyphosphate nanoparticles that
are able to overcome the enzymatic and mucus barriers providing a targeted drug release …

Biocides are widely used in water treatment for microbiological control. The rise of
antimicrobial resistance and the need to assure properly managed water systems require a …

Aim To evaluate the impact of polyethylene glycol (PEG) and zwitterionic surface decoration
of lipid-based nanocarriers (NC) on cellular uptake. Methods Anionic, neutral and cationic …

The hybrid heterocyclic scaffolds possess extensive medicinal values and significant
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …