[HTML][HTML] Antidotal or protective effects of Curcuma longa (turmeric) and its active ingredient, curcumin, against natural and chemical toxicities: A review
A Hosseini, H Hosseinzadeh - Biomedicine & pharmacotherapy, 2018 - Elsevier
Curcuma longa is a rhizomatous perennial herb that belongs to the family Zingiberaceae,
native to South Asia and is commonly known as turmeric. It is used as herbal remedy due to …
native to South Asia and is commonly known as turmeric. It is used as herbal remedy due to …
Polyphenols: Major regulators of key components of DNA damage response in cancer
DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …
damages. Cells that are affected by DNA damage employ a specific, intricate, and …
Amyotrophic lateral sclerosis and oxidative stress: a double-blind therapeutic trial after curcumin supplementation
L Chico, EC Ienco, C Bisordi, A Lo Gerfo… - CNS & Neurological …, 2018 - ingentaconnect.com
Objective: To investigate the efficacy of curcumin oral supplementation (600 mg/day,
Brainoil), a natural antioxidant compound, in Amyotrophic Lateral Sclerosis (ALS). Methods …
Brainoil), a natural antioxidant compound, in Amyotrophic Lateral Sclerosis (ALS). Methods …
Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: a review of molecular pathways
P Joshi, A Bisht, S Joshi, D Semwal… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin, isolated from turmeric (Curcuma longa L.) is one of the broadly studied
phytomolecule owing to its strong antioxidant and anti‐inflammatory potential and has been …
phytomolecule owing to its strong antioxidant and anti‐inflammatory potential and has been …
Therapeutic role of curcumin in diabetes: an analysis based on bioinformatic findings
Background: Diabetes is an increasingly prevalent global disease caused by the impairment
in insulin production or insulin function. Diabetes in the long term causes both microvascular …
in insulin production or insulin function. Diabetes in the long term causes both microvascular …
Add-on treatment with curcumin has antidepressive effects in Thai patients with major depression: results of a randomized double-blind placebo-controlled study
B Kanchanatawan, S Tangwongchai… - Neurotoxicity …, 2018 - Springer
Activation of immune-inflammatory and oxidative-nitrosative (IO&NS) stress pathways plays
a role in major depression (MDD). Evidence suggests that curcumin (500–1000 mg/day), a …
a role in major depression (MDD). Evidence suggests that curcumin (500–1000 mg/day), a …
A comprehensive review of mechanistic insights into formaldehyde-induced nasal cavity carcinogenicity
A Nishikawa, K Nagano, H Kojima, K Ogawa - Regulatory Toxicology and …, 2021 - Elsevier
Abstract According to the International Agency for Research on Cancer classification,
formaldehyde is a human carcinogen that targets the nasal cavity. In humans and rats …
formaldehyde is a human carcinogen that targets the nasal cavity. In humans and rats …
Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ
B Yang, C Yin, Y Zhou, Q Wang, Y Jiang, Y Bai, H Qian… - Toxicology, 2019 - Elsevier
Methylmercury (MeHg) is a ubiquitous environmental toxicant that leads to long-lasting
neurological deficits in animals and humans. Curcumin, a polyphenol obtained from the …
neurological deficits in animals and humans. Curcumin, a polyphenol obtained from the …
Genome-protecting compounds as potential geroprotectors
Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
Preemptive analgesic and antioxidative effect of curcumin for experimental migraine
Objective. Our study aimed to investigate the analgesic and antioxidative stress effects of
Curcumin (CC) in experimental migraine induced by Nitroglycerin (NTG) on rats, compared …
Curcumin (CC) in experimental migraine induced by Nitroglycerin (NTG) on rats, compared …