Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Developmental origins of health and disease: current knowledge and potential mechanisms

DJ Hoffman, RM Reynolds, DB Hardy - Nutrition reviews, 2017 - academic.oup.com
Epidemiologic and clinical research has provided a large body of evidence supporting the
developmental origins of health and disease (DOHaD), but there has been a relative dearth …

Persistent epigenetic differences associated with prenatal exposure to famine in humans

BT Heijmans, EW Tobi, AD Stein… - Proceedings of the …, 2008 - National Acad Sciences
Extensive epidemiologic studies have suggested that adult disease risk is associated with
adverse environmental conditions early in development. Although the mechanisms behind …

Birth weight and risk of type 2 diabetes: a systematic review

PH Whincup, SJ Kaye, CG Owen, R Huxley, DG Cook… - Jama, 2008 - jamanetwork.com
Context Low birth weight is implicated as a risk factor for type 2 diabetes. However, the
strength, consistency, independence, and shape of the association have not been …

[HTML][HTML] Genetics and epigenetics of obesity

BM Herrera, S Keildson, CM Lindgren - Maturitas, 2011 - Elsevier
Obesity results from interactions between environmental and genetic factors. Despite a
relatively high heritability of common, non-syndromic obesity (40–70%), the search for …

Prenatal famine and adult health

LH Lumey, AD Stein, E Susser - Annual review of public health, 2011 - annualreviews.org
We review human studies on the relation between acute exposures to prenatal famine and
adult physical and mental health. These studies are observational and include exposures to …

[HTML][HTML] Fetal programming and cardiovascular pathology

BT Alexander, JH Dasinger… - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Low birth weight serves as a crude proxy for impaired growth during fetal life and indicates a
failure for the fetus to achieve its full growth potential. Low birth weight can occur in …

Health and civil war in rural Burundi

T Bundervoet, P Verwimp, R Akresh - Journal of human Resources, 2009 - jhr.uwpress.org
We combine household survey data with event data on the timing and location of armed
conflicts to examine the impact of Burundi's civil war on children's health status. The …

Premature birth, low birth weight, small for gestational age and chronic non-communicable diseases in adult life: A systematic review with meta-analysis

ELSS de Mendonça, M de Lima Macêna… - Early human …, 2020 - Elsevier
Background Individuals who were born prematurely (PT), with low birth weight (LBW), or
small for gestational age (SGA) appear to present a set of permanent changes that make …

Biological mechanisms for nutritional regulation of maternal health and fetal development

G Wu, B Imhoff‐Kunsch… - Paediatric and perinatal …, 2012 - Wiley Online Library
This review paper highlights mechanisms for nutritional regulation of maternal health and
fetal development. Malnutrition (nutrient deficiencies or obesity) in pregnant women …