Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Anelloviridae and Redondoviridae are virus families with small, circular, single-stranded
DNA genomes that are common components of the human virome. Despite their small …

Purpose: To characterize the ocular surface microbiome of healthy volunteers using a
combination of microbial culture and high-throughput DNA sequencing techniques …

Background Drug-induced immunosuppression following kidney transplantation is crucial to
prevent allograft rejection, but increases risk for infectious disease. Tailoring of drug dosing …

Primary graft dysfunction (PGD) is a principal cause of early morbidity and mortality after
lung transplantation, but its pathogenic mechanisms are not fully clarified. To date, studies …

Viral primary infections and reactivations are common complications in patients after solid
organ transplantation (SOT) and hematopoietic stem cell transplantation (HSCT) and are …

Background Antibody-mediated rejection (AMR) represents one of the cardinal causes of
late allograft loss after kidney transplantation, and there is great need for noninvasive tools …

Torque teno viruses (TTV) are small DNA-viruses, of the genus Alphatorquevirus, whose
replication is linked to immune status. TTV load may be an indicator for efficacy of IS in lung …

Background The human Torque Teno virus (TTV) causes persistent viremia in most
immunocompetent individuals. Elevated TTV levels are observed after solid organ …

Background Drug-induced immunosuppression in kidney transplant recipients is crucial to
prevent allograft rejection, but increases risk for infectious disease. Immunologic monitoring …