Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene
studies have identified genetic variants associated with cardiovascular diseases, metabolic …

Bipolar disorder (BD) is strongly associated with immune dysfunction. Replicated
epidemiological studies have demonstrated that BD has high rates of inflammatory medical …

Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Beaulieu S, Alda M, O'Donovan C,
MacQueen G, McIntyre RS, Sharma V, Ravindran A, Young LT, Milev R, Bond DJ, Frey BN …

Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …

People with bipolar disorder frequently experience persistent residual symptoms, problems
in psychosocial functioning, cognitive impairment, and poor quality of life. In the last decade …

Objectives The study herein aimed to assess the prevalence of type 2 diabetes mellitus
(T2DM), impaired fasting glucose (IFG), as well as general and abdominal obesity in …

Methods For this narrative clinical overview, the MEDLINE/PubMed, Embase, Google
Scholar and ClinicalTrials. gov databases were searched from inception through June 2015 …

Objective: Therapeutic options are limited for treatment-resistant bipolar depression (TRBD).
Insulin resistance (IR) confers increased risk for TRBD. We investigated metformin, an …

Schizophrenia is frequently associated with obesity, which is linked with neurostructural
alterations. Yet, we do not understand how the brain correlates of obesity map onto the brain …

Metabolic syndrome (MetS) and its component factors, obesity, hypertension, dyslipidaemia
and insulin resistance, have shown a bidirectional relationship with the prevalence and …