Collaborative efforts from the fields of biology, materials science, and engineering are
leading to exciting progress in the development of nanomedicines. Since the targets of many …

Vesicular/membrane trafficking essentially regulates the compartmentalization and
abundance of proteins within the cells and contributes in many signalling pathways. This …

Alzheimer's disease is characterized by the progressive deposition of β-amyloid (Aβ) within
the brain parenchyma and its subsequent accumulation into senile plaques. Pathogenesis …

The involvement of the RAS superfamily of monomeric GTPases in carcinogenesis is
increasingly being appreciated. A complex array of post-translational modifications and a …

Rab proteins are best known for their essential roles in exocytic and endocytic membrane
trafficking, which encompass the constitutive and regulated secretory routes, endocytosis via …

Small GTPases of the Rab family control timing of vesicle fusion. Fusion of two vesicles can
only occur when they have been brought into close contact. Transport by microtubule‐or …

Cellular processes depend on the fidelity of intracellular membrane traffic. Lipids, proteins,
receptor ligands and solute molecules are trafficked to distinct compartments within the cell …

Coronavirus replication is facilitated by a number of highly conserved viral proteins. The
viruses also encode accessory genes, which are virus group specific and believed to play …

Quantitative mass spectrometry approaches are used for absolute and relative quantification
in global proteome studies. To date, relative and absolute quantification techniques are …

Emerging evidence implicates alterations in the RAB small GTPases and their associated
regulatory proteins and effectors in multiple human diseases including cancer. We have …