Clinical pancreatic islet transplantation can be considered one of the safest and least
invasive transplant procedures. Remarkable progress has occurred in both the technical …

Pancreatic islet transplantation has become an established approach to β-cell replacement
therapy for the treatment of insulin-deficient diabetes. Recent progress in techniques for islet …

Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem that affects one-
third of adults and an increasing number of children in developed countries. The disease …

Islet transplantation can restore endogenous β-cell function to subjects with type 1 diabetes.
Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their …

Nonalcoholic fatty liver disease (NAFLD) embraces the clinico-pathological consequences
of hepatic lipotoxicity and is a major public health problem globally. Sexual dimorphism is a …

Following the success obtained with transplantation of fresh human islets under steroid‐free
immunosuppression, this trial evaluated the transplantation of islets that had undergone a …

Glucose homeostasis is closely regulated not only by insulin, but also by leptin. Both
hormones act centrally, regulating food intake and adiposity in humans. Leptin has several …

Transplantation of pancreatic islets is a therapeutic option to preserve or restore β-cell
function. Our study was aimed at developing a clinically applicable protocol for extrahepatic …

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide.
Several lines of evidence have indicated a pathogenic role of insulin resistance, and a …

Abstract Objective Porcine islets of Langerhans for xenotransplantation into humans have
been proposed as a solution to the shortage of human donors. Rejection is one of the main …