Tissue engineered extracellular matrices (ECMs) in urology: Evolution and future directions

NF Davis, EM Cunnane, FJ O'brien, JJ Mulvihill… - the surgeon, 2018 - Elsevier
Autologous gastrointestinal tissue has remained the gold-standard reconstructive
biomaterial in urology for> 100 years. Mucus-secreting epithelium is associated with lifelong …

Bladder reconstruction: the past, present and future

O El‑Taji, AQ Khattak, SA Hussain - Oncology letters, 2015 - spandidos-publications.com
Ileal conduit urinary diversion is the gold standard treatment for urinary tract reconstruction
following cystectomy. This procedure uses gastrointestinal segments for bladder …

Recruitment of progenitor cells by an extracellular matrix cryptic peptide in a mouse model of digit amputation

V Agrawal, S Tottey, SA Johnson, JM Freund… - … engineering Part A, 2011 - liebertpub.com
Biologic scaffolds composed of extracellular matrix (ECM) have been used successfully in
preclinical models and humans for constructive remodeling of functional, site-appropriate …

Development of Enzymatic-Resistant and Compliant Decellularized Extracellular Matrixes via Aliphatic Chain Modification for Bladder Tissue Engineering

S Sharma, S Rajani, J Hui, A Chen… - … Applied Materials & …, 2022 - ACS Publications
Here, we report the design and development of highly stretchable, compliant, and enzymatic-
resistant transiently cross-linked decellularized extracellular matrixes (dECMs)(eg, porcine …

A comprehensive protein expression profile of extracellular matrix biomaterial derived from porcine urinary bladder

H Marçal, T Ahmed, SF Badylak, S Tottey… - Regenerative …, 2012 - Taylor & Francis
Aims: To generate a comprehensive profile of the protein composition of xenogeneic
biomaterial, derived from porcine urinary bladder matrix (UBM). Materials & methods: Tunica …

Urinary bladder vs gastrointestinal tissue: a comparative study of their biomechanical properties for urinary tract reconstruction

NF Davis, JJE Mulvihill, S Mulay, EM Cunnane… - Urology, 2018 - Elsevier
Objective To evaluate the mechanical properties of gastrointestinal (GI) tissue segments and
to compare them with the urinary bladder for urinary tract reconstruction. Methods Urinary …

[HTML][HTML] Non-muscular invasive bladder cancer: re-envisioning therapeutic journey from traditional to regenerative interventions

KW Shih, WC Chen, CH Chang, TE Tai, JC Wu… - Aging and …, 2021 - ncbi.nlm.nih.gov
Non-muscular invasive bladder cancer (NMIBC) is one of the most common cancer and
major cause of economical and health burden in developed countries. Progression of …

Development of a porcine acellular bladder matrix for tissue-engineered bladder reconstruction

M Garriboli, K Deguchi, G Totonelli… - Pediatric Surgery …, 2022 - Springer
Purpose Enterocystoplasty is adopted for patients requiring bladder augmentation, but
significant long-term complications highlight need for alternatives. We established a protocol …

A mathematical model for analyzing the elasticity, viscosity, and failure of soft tissue: comparison of native and decellularized porcine cardiac extracellular matrix for …

T Bronshtein, GCT Au-Yeung, U Sarig… - … Engineering Part C …, 2013 - liebertpub.com
The clinical success of tissue-engineered constructs commonly requires mechanical
properties that closely mimic those of the human tissue. Determining the viscoelastic …

Biomaterials and regenerative medicine in urology

NF Davis, EM Cunnane, MR Quinlan… - Cell Biology and …, 2018 - Springer
Autologous gastrointestinal tissue is the gold standard biomaterial for urinary tract
reconstruction despite its long-term neuromechanical and metabolic complications …