Measurements of cardiac conduction velocity provide valuable functional and structural
insight into the initiation and perpetuation of cardiac arrhythmias, in both a clinical and …

Over 7 million people worldwide die annually from erratic heart rhythms (cardiac
arrhythmias), and many more are disabled. Yet there is no imaging modality to identify …

A bidomain reaction-diffusion model of the human heart was developed, and potentials
resulting from normal depolarization and repolarization were compared with results from a …

We have previously developed a canine in vivo model of the long QT syndrome (LQTS)
using the neurotoxin anthopleurin A (AP-A), which acts by slowing sodium channel …

To characterize the role of the gap junction protein connexin43 (Cx43) in ventricular
conduction, we studied hearts of mice with targeted deletion of the Cx43 gene. Mice …

Implantable Cardioverter Defibrillators. Antiarrhythmic drugs and separate bradycardia
pacing systems are prescribed commonly in patients with implantable cardioverter …

Background—Endocardial mapping is mandatory before radiofrequency catheter ablation
(RFCA). Mapping can be performed with either unipolar or bipolar recordings. Impact of the …

The expanded guide to cardiac mapping The effective diagnosis and treatment of heart
disease may vitally depend upon accurate and detailed cardiac mapping. However, in an …

Background—Ripple mapping (RM) displays each electrogram at its 3-dimensional
coordinate as a bar changing in length according to its voltage–time relationship with a …

Activation Time Determination by High‐Resolution Electrograms. Introduction: To identify the
optimal criteria for activation time (AT) determination of bipolar electrograms from normal …