Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …
[HTML][HTML] Diabetic neuropathy: a position statement by the American Diabetes Association
R Pop-Busui, AJM Boulton, EL Feldman, V Bril… - Diabetes …, 2017 - ncbi.nlm.nih.gov
Diabetic neuropathies are the most prevalent chronic complications of diabetes. This
heterogeneous group of conditions affects different parts of the nervous system and presents …
heterogeneous group of conditions affects different parts of the nervous system and presents …
Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management
TS Jensen, P Karlsson, SS Gylfadottir, ST Andersen… - Brain, 2021 - academic.oup.com
Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …
Peripheral neuropathy in diabetes mellitus: pathogenetic mechanisms and diagnostic options
R Galiero, A Caturano, E Vetrano, D Beccia… - International Journal of …, 2023 - mdpi.com
Diabetic neuropathy (DN) is one of the main microvascular complications of both type 1 and
type 2 diabetes mellitus. Sometimes, this could already be present at the time of diagnosis …
type 2 diabetes mellitus. Sometimes, this could already be present at the time of diagnosis …
The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes
Small fibre neuropathies are a heterogeneous group of disorders affecting thinly myelinated
Aδ-fibres and unmyelinated C-fibres. Although multiple causes of small nerve fibre …
Aδ-fibres and unmyelinated C-fibres. Although multiple causes of small nerve fibre …
Peripheral neuropathy in prediabetes and the metabolic syndrome
AM Stino, AG Smith - Journal of diabetes investigation, 2017 - Wiley Online Library
Peripheral neuropathy is a major cause of disability worldwide. Diabetes is the most
common cause of neuropathy, accounting for 50% of cases. Over half of people with …
common cause of neuropathy, accounting for 50% of cases. Over half of people with …
Diagnostic criteria for small fibre neuropathy in clinical practice and research
G Devigili, S Rinaldo, R Lombardi, D Cazzato… - Brain, 2019 - academic.oup.com
The diagnostic criteria for small fibre neuropathy are not established, influencing the
approach to patients in clinical practice, their access to disease-modifying and symptomatic …
approach to patients in clinical practice, their access to disease-modifying and symptomatic …
The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy
Disabling neuropathic pain (NeuP) is a common sequel of diabetic peripheral neuropathy
(DPN). We aimed to characterise the sensory phenotype of patients with and without NeuP …
(DPN). We aimed to characterise the sensory phenotype of patients with and without NeuP …
Metabolic syndrome and peripheral neuropathy
M Kazamel, AM Stino, AG Smith - Muscle & Nerve, 2021 - Wiley Online Library
Diabetic peripheral neuropathy and metabolic syndrome (MetS) are both global health
challenges with well‐established diagnostic criteria and significant impacts on quality of life …
challenges with well‐established diagnostic criteria and significant impacts on quality of life …
Advances in screening, early diagnosis and accurate staging of diabetic neuropathy
J Carmichael, H Fadavi, F Ishibashi… - Frontiers in …, 2021 - frontiersin.org
The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …